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Pharmacognosy 2018

American Journal of Ethnomedicine

ISSN: 2348-9502

Page 97

April 16-17, 2018

Amsterdam, Netherlands

6

th

Edition of International Conference on

Pharmacognosy and

Medicinal Plants

Antimicrobial activities of total crude saponins from Parinari

curatellifolia planch ex. Benth root bark

Halilu M E, Ifeanyi G I

and

Ungokore H Y

Usmanu Danfodiyo University, Nigeria

Am J Ethnomed 2018, Volume 5

DOI: 10.21767/2348-9502-C1-006

T

he roots of

Rhus mysorensis

of

Anacardiaceae

family is used

by the tribes of Andhra Pradesh, India, for the treatment of

varioushepaticdisorders. In thisstudy, the root of

Rhusmysorensis

was selected for the investigation of its hepatoprotective activity

against CCl4 induced hepatotoxicity. The rats were given a daily

pre-treatment with ethyl acetate

Rhus mysorensis

root 200, 400

and 800 mg/kg and silymarin (25 mg/kg) followed by CCl4 at a

dose of 1.25 ml/kg orally for seven days. On the eighth day, blood

was collected from the reto orbital plexus of all the rats. Serum

was separated by centrifugation and analyzed for serum glutamic

pyruvate transaminase (SGPT), serum glutamic oxaloacetic

transaminase (SGOT), alkaline phosphatase (ALKP), cholesterol

(CHL), total protein (TPTN) and albumin (ALB). The result of

the present study suggests that ethyl acetate extract of

Rhus

mysorensis

root showed better hepatoprotective activity due to

the presence of phytoconstituents such as steroids, triterpenoids

and flavonoids. Thus, the present study provides a scientific and

rational for the traditional use of this plant on the management of

liver diseases.

pharmplants@gmail.com

Hepatoprotective activity of Rhus mysorensis root extract on

carbon tetrachloride induced hepato-toxicity in Wistar rats

Prabhakar T

and

D Baggiyaselvi

Karnataka College of Pharmacy, India