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Pharmacognosy 2018
American Journal of Ethnomedicine
ISSN: 2348-9502
Page 53
April 16-17, 2018
Amsterdam, Netherlands
6
th
Edition of International Conference on
Pharmacognosy and
Medicinal Plants
I
n the present study, the antihyperglycemic, hypolipidemic and
antioxidant properties of the specially formulate polyherbal
formulation in streptozotocin induced diabetic rats was
determined. Diabeteswas induced in albino rats by administration
of streptozotocin (55mg/kg, I.P).The formulationF1 (N:G:S=2:2:1)
200 mg/kg body weight was administered to diabetes induced
rats for a period of 28 days, which possess better effect than
formulation F2 (N:G:S=2:1:2) 200 mg/kg and formulation F3
(N:G:S=2:1:1) 200 mg/kg. Additional biochemical parameters
such as serum cholesterol, triglycerides, HDL-cholesterol, LDL-
cholesterol levels were also measured at the ending of study.
After verifying the antidiabetic property, the F1 (N:G:S=2:2:1) 200
mg/kg in blood glucose was observed for the finest one; in order
to justify it we have to check its oxidative parameter, i.e. SOD,
TBAR, GSH and LPO, which enzyme indicates its oxidative stress.
From the above outcome, it was concluded that the formulation
F1 (N: G: S =2:2:1) 200 mg/kg on blood glucose possesses
significant antidiabetic, hypolipidemic and antioxidant effects in
streptozotocin induced diabetic rats.
Biography
JhanseeMishra received her BPharmandMPharm from Indira Gandhi Institute of
Pharmaceutical Sciences (IGIPS), Bhubaneswar, Odisha. She was awarded PhD
Degree in Pharmaceutical Sciences from Suresh Gyan Vihar University (SGVU),
Jaipur, Rajasthan, India. She is working as an Assistant Professor at the Insti-
tute of Pharmacy, Veer Bahadur Singh Purvanchal University, India. Her present
research projects are focused on “polyherbal formulation and standardization of
selected few medicinal plants having antidiabetic activity”. She has more than 30
national and international publications and two books to her credit. She has nine
years of experience in research and teaching. She is Regional Editor in
Internation-
al Research Journal of Pharmacy
, Member of the Central Executive Committee
Journal of Scientific Letters. She is life member of Indian Community Pharmacy
and has organized many national and international conferences and workshops.
email2jhansi@yahoo.co.inPolyherbal formulation of selected few medicinal plants
having antidiabetic activity
Jhansee Mishra
Veer Bahadur Singh Purvanchal University, India
Jhansee Mishra, Am J Ethnomed 2018, Volume 5
DOI: 10.21767/2348-9502-C1-005