nano-congress-nano-drug-delivery-2018-posters

Volume 4

Nano Research & Applications

ISSN: 2471-9838

Page 93

JOINT EVENT

August 16-18, 2018 | Dublin, Ireland

Edition of International Conference on

Nanopharmaceutics and Advanced Drug Delivery

Nano Congress for

Future Advancements

Nano Congress 2018

Nano Drug Delivery 2018

August 16-18, 2018

Microemulsion routes to nanomaterials of controlled size and toxicity

M.Worsley, A.Sireetharan

and

P.A.Sermon

Brunel University, UK

he extent to which NPs are bound onto or into macro matrices by say chemical glues [1] affects their availability and health-

environmental impact. The toxicity of NPs has an important impact on human health and the environment. This can from

their high surface: volume ratio (i.e. their particle size), but also their morphology, degree of aggregation and concentration

[2], and because of all these they interact uniquely with their surrounding environment. Often their toxicity increases as their

size decreases, possibly due to their (i) ease of penetration of cell walls, (ii) higher solubility and vapour pressure (via the

Kelvin equation), (iii) higher reactivity with larger number of defects and lower number of nearest neighbours (N) and (iv)

low stability metastable structures. Their higher toxicity in seen in reference [3]. It ought to relate to particle size effects seen

in other spheres of chemistry, e.g. catalysis of structure -sensitive and –insensitive reactions over small metal particles noted at

Brunel in the 1980s [1]. For example growth of Ru NPs can at intermediate sizes produce B5-sites. Fractal analysis [4]; surface

geometries can overshadow surface chemistry. Fractal analysis is a tool for investigating these complex structures. If the surface

has n sites of area σ then the surface area A=n

. Here we consider the opportunities provided by non-ionic surfactant (NIS)-

stabilized water-in-oil microemulsions to produce designer nanoparticles of metals, oxides, perovskites and nanocomposites.

In this area France has a long heritage [5].

Nano Res Appl 2018, Volume 4

DOI: 10.21767/2471-9838-C3-015