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Volume 4
Nano Research & Applications
ISSN: 2471-9838
Page 88
JOINT EVENT
August 16-18, 2018 | Dublin, Ireland
&
12
th
Edition of International Conference on
Nanopharmaceutics and Advanced Drug Delivery
25
th
Nano Congress for
Future Advancements
Nano Congress 2018
&
Nano Drug Delivery 2018
August 16-18, 2018
Nano Res Appl 2018, Volume 4
DOI: 10.21767/2471-9838-C3-015
Biological study of some first series transition metal complexes with adenine ligand
Hamad M I Hasan
1
, Aaza I Yahiya
1
, Safaa S Hassan
2
and
Mabrouk M Salama
3
1
Omar Al-Mukhtar University, Libya
2
Cairo University, Egypt
3
University of Benghazi, Libya
A
denine complexes were prepared with some of the first series transition metals in a stoichiometric ratio of 1:2 ( Mn+: L),
where Mn
+
= Mn
2+
, Fe
3+
, Co
2+
, Ni
2+
, Cu
2+
, Zn
2+
, and Cd
2+
ions. The complexes were characterized by the physicochemical
and spectroscopic techniques as electric conductivity, metal contents, IR, UV–visible, and molar conductance techniques. The
stoichiometric ratios of the synthesized complexes were confirmed by using molar ratio method. The dissociation constant
of adenine ligand was determined spectrophotometrically. Solvent effect on the electronic spectra of the adenine ligand was
examined using solvents with different polarities. The biological activity of adenine ligand and its metal complexes were tested
in vitro
against some selected species of fungi and bacteria. The results showed a satisfactory spectrum against the tested
organisms.
mabrouk.salama@uob.edu.ly