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Volume 3, Issue 3 (Suppl)
J Obes Eat Disord
ISSN: 2471-8203
Obesity Medicine 2017
October 30-31, 2017
October 30-31, 2017 Bangkok, Thailand
15
th
International Conference on
Obesity Medicine
Clinical scenario of primary dyslipidemia in the pediatric age group: An Egyptian experience
Rania Hosny Tomerak
Cairo University Children’s Hospital, Egypt
Objectives:
To study the frequency of occurrence of the different forms of primary dyslipidemia and to display their various
clinical presentations and their lipid profile before and six months after therapy.
Methods:
Prospective study was conducted in the Cairo University Children’s Hospital-20 primary dyslipidemic cases were
included with history taking, clinical examination, electrocardiography and echocardiography. Investigations included: Total
cholesterol, total triglycerides, LDL-C and HDL-C using enzymatic colorimetric methods, ApoA1, Apo B100 were evaluated
using a Behring nephelometer. Different therapeutic modalities were offered and reassessment of laboratory tests was done
every three months.
Results:
Parents were consanguineous in 75% cases. Eleven cases had hypercholesterolemia; eight had xanthoma, one had
xanthelasma, two had hypo-pigmentation, three had corneal arcus, one had lipaemia retinalis and six had cardiacmanifestations
among which one case had myocardial infarction and one case died. Three cases had hypertriglyceridemia; three had milky
plasma, two had xanthoma, two had lipaemia retinalis, one case had pancreatitis and none had cardiac manifestations. Six
cases had mixed hyperlipidaemia; five had xanthoma, three had lipaemia retinalis and two had cardiac manifestations. After
six months of multi-drug use, the laboratory lipid profile was unsatisfactory in majority of the cases.
Conclusion:
Primary dyslipidemia may present in early and pediatricians should have high index of suspicion. These children
should be put on early strict lipid reduction protocols to prevent complications.
raniatomerak@yahoo.comJ Obes Eat Disord 2017, 3:3
DOI: 10.21767/2471-8203-C1-006