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.com
Volume 3, Issue 3 (Suppl)
J Obes Eat Disord
ISSN: 2471-8203
Obesity Medicine 2017
October 30-31, 2017
October 30-31, 2017 Bangkok, Thailand
15
th
International Conference on
Obesity Medicine
Dose and source of calcium regulates postprandial glycemic and satiety responses in healthy young
male subjects
Muhammad Umair Arshad, Ali Imran, Farhan Saeed, Ambreen Naz, Sajid Arshad and Madeeha Ilyas
Government College Women University, Pakistan
H
igh dairy or calcium intake has been linked to reduced insulin resistance, however, the role of calcium amount and
source is not explored. Therefore, the present study was conducted to examine the effects high and low levels of calcium
carrying dairy products coming from natural as well supplement sources on glucose homeostasis as well appetite regulation.
In a randomized, cross-over design, 20 healthy males (20-30Y) were provided two iso-caloric servings (250 ml) of either: 1)
High calciummilk (HCM; Nesvita Ca-Plus; 500 mg Ca) or 2) Low calciummilk (LCM; Nestle Milkpak; 250 mg Ca) or 3) High
calcium simulated milk beverage (HCS; 500 mg calcium carbonate) or 4) Low calcium simulated milk beverage (LCS; 250 mg
Calcium carbonate). Following the treatments, subjects were served an ad libitum pizza meal at 120 min to assess the food
intake. Following which blood glucose (BG), average subjective appetite (ASA), serum insulin and satiety related hormones
(GLP-1, active ghrelin) were evaluated at different time intervals. The BG concentration was reduced (P<0.0001) following
HCM compared with all others, without disproportionate increase in insulin. Higher calcium levels were observed to reduce
BG levels compared with their lower counterpart (P=0.0002). However, post-treatment avg. subjective appetite (P=0.0017)
and food intake (P=0.0021) were significantly reduced due to amount of calcium, but not source of calcium. HCM further
significantly improved GLP-1 concentration (P<0.0001), without any effect on active ghrelin. Both amount and source of
calcium regulate glycemic responses, while satiety responses were only regulated through amount of calcium but not its source.
umairfood1@gmail.comJ Obes Eat Disord 2017, 3:3
DOI: 10.21767/2471-8203-C1-006