immunology-research-tissue-science-2018-posters

20 / 26

Journal of Transmitted Diseases and Immunity
ISSN: 2573-0320 Page 79
Volume 4
May 10-11, 2018
Frankfurt, Germany
Immunology Research 2018
Tissue Science 2018
JOINT EVENT
2 2 n d E d i t i o n o f I n t e r n a t i o n a l C o n f e r e n c e o n
Immunology and
Evolution of Infectious Diseases
&
1 2 t h E d i t i o n o f I n t e r n a t i o n a l C o n f e r e n c e o n
Tissue Engineering and
Regenerative Medicine
T he objective of this study was to obtain three-dimensionally
(3D) printed scaffolds from nano-sized calcium phosphate
(amorphous calcium phosphate; ACP) and polycaprolactone
(PCL) ink for bone tissue regeneration (BTR). The synthesis of the
nano-sized calcium phosphate was performed by wet method.
The material was characterized by X-ray diffraction (XRD),
infrared spectroscopy (FTIR), scanning electron microscopy
(SEM) and determination of the surface area by adsorption of
nitrogen. After obtaining the ink, cylindrical scaffolds (15x10mm)
were 3D printed. Mechanical strength, SEM, EDX and porosity
were evaluated. Results of XRD analysis showed an intense
peak at θ=23.4 corresponding to ACP, as well as other peaks of
lower intensities corresponding to HA, ACP and OCP. The FTIR
spectrum confirmed that the sample obtained corresponded to
the nano-sized calcium phosphate sample. Studies of viscosity
showed that the composition of nano-sized calcium phosphate
and PCL used was suitable for the preparation of the ink. The
SEM analysis shows that the post-printed material maintains the
cylindrical structure. It is also observed interconnected pores. On
the other hand, the EDX analysis showed the presence of calcium
and phosphorus. The analysis of microstructural characterization
using the mercury intrusion porosimetry method showed that
the porosity was around 70%. The mechanical resistance studies
showed values within the range established for this type of
material. The nano-sized calcium phosphate obtained through
the synthesis process has the necessary quality to be used in the
production of inks for 3D printing employed in BTR.
3D printing technology: study based on nano-sized calcium
phosphate and PCL ink for bone tissue regeneration
Fernando Pozzi Semeghini Guastaldi
Massachusetts General Hospital, USA
J Transm Dis Immun 2018, Volume 2
DOI: 10.21767/2471-8084-C1-003