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Pharmacognosy 2018
American Journal of Ethnomedicine
ISSN: 2348-9502
Page 27
April 16-17, 2018
Amsterdam, Netherlands
6
th
Edition of International Conference on
Pharmacognosy and
Medicinal Plants
A
novel herbal aerosol spray formulation containing
methanol leaf extracts of
Cardiospermum halicacabum
(MLECH) and
Vitex negundo
(MLEVN) was formulated using
MLECH and MLEVN (2% w/v each) and their quality control,
stability and efficacy studies were carried out as per the
United States Pharmacopoeia (USP), International Conference
on Harmonization (ICH) and Organization for Economic Co-
Operation and Development (OECD) guidelines, respectively.
Complete Freund’s adjuvant (CFA) induced arthritis method
was employed for the evaluation of anti-arthritic activity.
Assessment of body weight, biochemical parameters,
hematological parameters, serum biomarker levels,
photographic, radiographic analysis and histopathological
investigations were carried out as a supportive evidence
for the anti-arthritic efficacy of the developed novel herbal
aerosol spray formulation. The results of the quality control
test complied with USP standards and the stability study
clearly revealed that the formulated topical herbal aerosol
spray was found to be stable. Significant (p<0.01) alterations
in rat paw volume, body weight, biochemical, hematological,
serum biomarker levels and reduction in inflammation and
hyperplasia of synovium of formulation treated rats were
observed compared with arthritic rats. The study concluded
that the formulated novel herbal aerosol spray exhibited good
anti-arthritic activity.
Biography
Rajasekaran Aiyalu is a Professor of KMCH College of Pharmacy and has
more than 28 years of teaching and research experience in the field of Phar-
macy. He has received research grants from various Government agencies
like DSIR, DST, DRDO and AICTE, etc. He has 5 patents to his credit. He has
published 84 research papers in international and 134 research papers in
national peer reviewed journals. He has visited Malaysia, Singapore, Thai-
land, Philippines, Sri Lanka, UAE and presented papers in various national
and international conferences. He has received Best Teacher Award from
the Tamilnadu Dr. M G R Medical University, Chennai.
rsekaran2001in@yahoo.co.inFormulation and evaluation of novel herbal aerosol for arthritis
Rajasekaran Aiyalu
1
, Ithyaventhan Subramaniam
2
, Arulkumaran Govindarajan
1
and
Arivukkarasu Ramasamy
1
1
KMCH College of Pharmacy, India
2
Doctor Thangs Products, India
Rajasekaran Aiyalu et al., Am J Ethnomed 2018, Volume 5
DOI: 10.21767/2348-9502-C1-005