obesity-2018-scientifictracks-abstracts

t h

E u r o p e a n C o n g r e s s o n

Obesity and

Eating Disorder

Obesity 2018

Journal of Obesity & Eating Disorders

ISSN 2471-8203

A p r i l 1 2 - 1 3 , 2 0 1 8

Am s t e r d a m , N e t h e r l a n d s

Page 27

ariatric surgery is now advocated as a treatment option for type 2 diabetes.

The pathophysiology of improved glycaemic control after these procedures

is not fully elucidated. Bile acids have traditionally been considered mediators

of lipid absorption and cholesterol metabolism. However, in recent years bile

acids have been identified as metabolic molecules which play a significant part

in glucose metabolism amongst others. The metabolic effects are mediated by

activating the nuclear receptor, farnesoid X receptor (FXR) and the G protein-

coupled membrane receptor (TGR5) which may in part attribute to the long

term remission of type 2 diabetes. This session will provide an overview of the

relationship between bile acids and incretin hormones, laboratory analysis of

bile acids as well as explore how altered bile acid metabolism after bariatric

surgery can improve glycaemic control.

Biography

Royce P Vincent is a Consultant Chemical Pathologist at King’s

College Hospital NHS Foundation Trust and an Honorary Senior

Lecturer at King’s College London, UK. He is the Clinical Lead

for Biochemistry and Parenteral Nutrition services. He obtained

his MD (Res) at Imperial College London. His research interests

are in Obesity, Endocrinology and Clinical Nutrition. He has pub-

lished over 45 original research and review articles and is serv-

ing as an International Editorial Board Member for

Translational

Metabolic Syndrome Research

Altered bile acid metabolism after bariatric surgery and glycaemic

control

Royce P Vincent

King’s College Hospital NHS Foundation Trust, London, UK

Royce P Vincent, J Obes Eat Disord 2018, Volume: 4

DOI: 10.21767/2471-8203-C1-008