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Journal of Medical Physics and Applied Sciences
ISSN: 2574-285X
I n t e r n a t i o n a l C o n f e r e n c e o n
Nuclear Medicine &
Radiation Therapy
Nuclear Medicine & Radiation Therapy 2018
O c t o b e r 0 1 - 0 2 , 2 0 1 8
S t o c k h o l m , S w e d e n
Absolute quantification of myocardial blood flow (MBF) by PET is an established method of analysing coronary artery disease,
but the limited availability of radiotracers is the main shortcoming. Myocardial perfusion imaging (MPI) by SPECT is the standard
method of evaluating myocardial ischemia, but here the diagnosis is made mainly by visual analysis, rather than quantitation.
Furthermore, extensive ischemia in patients with multi-vessel disease is often difficult to diagnose in a relative perfusion
distribution pattern in SPECT. A new SPECT camera equipped with cadmium zinc telluride crystals not only has been shown
improved spacial resolution, but also potential for dynamic perfusion analysis. From this dynamic scan, MBF as well as myocardial
flow reserve (MFR) can be calculated. It still remains unclear wether MBF and MFR measured from SPECT can be used in clinical
practice to recognise all critical coronary lesions, which need an appropriate coronary intervention.
pieter.de.bondt@gmail.comQuantitative perfusion in cardiac SPECT imaging:
fiction or fact?
Pieter De Bondt, Dirk Ooms, Olivier De Winter
PET Centre South-East Flanders-OLV Hospital Aalst, Belgium
J. med phys & appl sci 2018, Volume: 3
DOI: 10.21767/2574-285X-C1-003