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E u r o S c i C o n C o n f e r e n c e o n
Chemistry
2018
Chemistry 2018
Journal of Organic & Inorganic Chemistry
ISSN 2472-1123
F e b r u a r y 1 9 - 2 0 , 2 0 1 8
P a r i s , F r a n c e
Page 49
W
ith approximately 80% of the World's population relying on traditional
medicine, researchers have turned towards bioactive compounds from
natural sources, identifying, over the years, many valuable tools to fight both
chronic and infectios diseases. Aquatic plants have a long and rich history
in this field, with species of the
Nymphaeaceae
family being involved in the
treatment of diabetes, liver and renal pathologies and inflammation. The aim
of this study was to extract, identify and analyse bioactive compounds in
Nymphaea alba
, harvested from the Lower Prut Low Meadow Natural Park in
Romania but otherwise widespread across Europe. Methanolic extracts were
obtained from Nymphaea alba roots. Their antioxidant activity was evaluated
using the DPPH scavenging and β-carotene bleaching methods and the total
polyphenol and flavonoid content was analysed. Various compounds were
separated, identified and quantified using the HPLC-MS technique. Results
have shown a polyphenol concentration of over 10 mg gallic acid equivalent per
100 mg root extract, subsequently exhibiting an IC50 DPPH scavenging effect
at 5 µg/mL. Mass spectra have shown fragments assigned to compounds
such as: hexahydroxydiphenolic, chlorogenic and tannic acids, epicatechin,
corilagin and other bioactive compounds. In conclusion,
Nymphaea alba
roots
are a rich source of compounds, prompting further research to elucidate the
mechanisms and confirm the pharmacological potential of this aquatic plant.
Biography
Ioana O Ghinea obtained her PhD in Biotechnology from the
“Dunărea de Jos” University of Galați after a BSc degree in
Chemistry from the University of Bucharest, In the same year
she joined the Department of Chemistry, Physics and Envi-
ronment from “Dunărea de Jos” University of Galați, Romania,
where she is now, Lecturer in the fields of Organic and Food
Chemistry. She has published 2 book chapters and over 10
scientific papers. Her research is focused on green chemistry,
biocatalysis and also on the determination of biological activity
(antimicrobial, antioxidant, enzyme inhibition, protein interac-
tion, etc.) of synthetic and natural products.
ioana.ghinea@ugal.roNymphaea alba – a valuable and untapped source of bioactive
compounds
Ioana O Ghinea, Mihaela Cudălbeanu, Bianca Furdui and
Rodica M. Dinica
“Dunarea de Jos” University of Galati, Romania
Ioana O Ghinea, J Org Inorg Chem 2018, Volume: 4
DOI: 10.21767/2472-1123-C1-003