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August 17-18, 2017 | Toronto, Canada

ANNUAL BIOTECHNOLOGY CONGRESS

Ann Biol Sci, 2017

ISSN: 2348-1927

I

maging is a fundamental tool in the practice of medicine.

The interaction of medical imaging radiation with new

materials has long been exploited to develop new and

improved imaging systems and techniques. In parallel with

these advances, there is increasing interest in developing

new contrast agents for the diagnosis of disease. Exogenous

contrast agents are non-native sources of contrast that

differentially scatter, absorb, or emit medical imaging

radiation (e.g., sound waves for ultrasound imaging,

radiofrequency waves for magnetic resonance imaging,

near IR light for photoacoustic imaging, and x-rays for

computed tomography and mammography) as compared

to surrounding tissues and inherent background noise such

that their location can be tracked upon introduction into a

patient. At the forefront of new contrast agent development

are new, clinically-relevant, materials that can be activated

by medical imaging radiation external to the patient and

under image guidance, to characterize and treat cancer.

Since the contrast agents’

in-vivo

distribution and interaction

with radiation are strongly size- and material-dependent,

a new opportunity in engineering is the creation of new

nanoscale systems that can be tailored for specific contrast

imaging and with therapeutic properties. This talk will focus

on the development of new perfluorocarbon agents that

can facilitate more focused and targeted delivery of cancer

therapies to tumours for higher therapeutic ratios, and can

permit the treatment of hard-to-access organs like the brain

in a minimally-invasive manner

Speaker Biography

Dr. Naomi Matsuura, PhD, P.Eng., is currently an Associate Professor in Materials

Science & Engineering and the Institute of Biomaterials & Biomedical Engineering

(IBBME) with a cross-appointment in Medical Imaging at the University of Toronto.

Dr. Matsuura leads a research program at the intersection of nanoengineering and

medicine, focusing on the design of new contrast agents to guide the imaging and

treatment of disease. Awards and recognitions include the John C. Polanyi Prize in

Physiology/Medicine and Physics, an NSERC Discovery Accelerator Award, and the

Early Researcher Award from the Ontario Ministry of Research and Innovation.

e:

naomi.matsuura@utoronto.ca

Engineering biomaterials for medical imaging of cancer

Naomi Matsuura

University of Toronto, Canada

Naomi Matsuura, Ann Biol Sci, 2017, 5:3

DOI: 10.21767/2348-1927-C1-002