Page 38
Nano Research & Applications
ISSN 2471-9838
September 11-12, 2017 Amsterdam, Netherlands
20
th
International Conference on
Advanced Nanotechnology
Notes:
Advanced Nano 2017
Nanoscale engineering of plasmonic materials
for biosensing
E
arly diagnosis plays an increasingly significant role
in current clinical drive. Detection, identification, and
quantification of low abundance biomarker proteins
form a promising basis for early clinical diagnosis and
offer a range of important medical benefits. Amplification
of light from NIR fluorophores by coupling to metal
nanostructures, i.e. Metal Induced Fluorescence
Enhancement (MIFE), represents a promising
strategy for dramatically improving the detection and
quantification of low abundance biomarker proteins,
and potentially increase already sensitive fluorescence
based detection by up to three orders of magnitude. The
amplification of the fluorescence system is based on
interaction of the excited fluorophores with the surface
plasmon resonance in metallic nanostructures. The
enhanced fluorescence intensity due to the existence of
metal nanostructures makes it possible to detect much
lower levels of biomarkers tagged with fluorescence
molecules either in sensing format or for tissue imaging.
The first part of my talk will focus on some recent
developments of plasmonic metal nanostructures
by both top-down and bottom up methods. I will then
discuss the prepared plasmonic nanostructures in the
applications of biosensing.
Biography
Fang Xie is a Senior Lecturer in Department of Materials, Imperial College London.
She is also Deputy Director. She has expertise in functional nanomaterials
including metal, semiconducting, and oxide nanomaterials synthesis, as well as
the applications of the functional materials in energy and life sciences. Her current
research interests include plasmonic nanostructures for efficient light harvesting for
solar cells and solar fuels, as well as in ultrasensitive biosensing and bio-imaging
applications. She has over 50 publications including five patents.
f.xie@imperial.ac.ukFang Xie
Imperial College London, UK
Fang Xie, Nano Res Appl 2017, 3:3
DOI: 10.21767/2471-9838-C1-001