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Pharmacognosy 2019
March 11-12, 2019
London, UK
American Journal of Ethnomedicine
ISSN: 2348-9502
Page 47
Pharmacognosy and
Medicinal Plants
7
th
Edition of International Conference on
Am J Ethnomed 2019, Volume 6
DOI: 10.21767/2348-9502-C1-009
Chemistry and medicinal properties of
Erythrina brucei
(A medicinal plant of Ethiopia)
Getahun Tadesse Gurmessa I B
and
Masessane R R T
Majinda Wollega University, Ethiopia
E
rythrian brucei is a tree grown only in Ethiopia. It
grows up to the height of 15-20 m long with colorful
flowers. In different parts of the country the root and
stem bark of this plant is used to treat ear infection and
other diseases. Previous studies revealed that the flower
and seed of
E. brucei
contain biologically active alkaloids;
however, there was no report for the nonalkaloidal
constituents of this plant. Recently, however we did a
comprehensive phytochemical investigation on root
bark, stem bark and twigs of the plant concentrated
on nonalkaloidal compounds. In the study, we isolated
biologically significant compounds and come up with
two new compounds which were not isolated so far
from the nature. The identities of the compounds were
established based on spectrometric and spectroscopic
analysis including MS, 1D and 2D NMR. Resazurin
based antibacterial minimum inhibitor concentration
(MIC) and DPPH antioxidant assay were carried out on
some selected compounds using standard references
chloramphenicol and trolox respectively. The tested
compounds showed promising antibacterial activity up
to (IC50 = 0.0625mg/mL) and antioxidant activity (IC50 =
1.1μg/mL) comparable to standard references.