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Pain Management 2019 & Internal Medicine 2019 International Journal of Anesthesiology & Pain Medicine
ISSN: 2471-982X Page 74
JOINT EVENT
7th Edition of International Conference on
Pain Management
8th Edition of International Conference on
Internal Medicine &
Patient Care
&
March 25-26, 2019
Rome, Italy
Int J Anesth Pain Med 2019, Volume 5
DOI: 10.21767/2471-982X-C1-006
Iron metabolism of proteins during pregnancy
I J Shahverdiyeva, I A Kerimova and V I Yaqubova
Azerbaijan Medical University, Azerbaijan
The high prevalence of anaemia in pregnant women
is an extremely urgent problem of medicine. Iron
deficiency anaemia (IDA) is the most common form
among pregnant anaemia and is about 90% [1]. IDA
leads to adverse consequences for both the pregnant
woman (an increase in the frequency of preterm
birth, placental insufficiency; miscarriage; infectious
complications, gestasional depression) and for the fetus
(fetal malnutrition). To study the pathogenesis of IDA
in pregnant women is important for the developing of
new principles of treatment. We study some indicators
of iron metabolism in pregnant women in anaemia. The
venous blood of 85 pregnant women with anaemia was
examined. Serum iron, ferroportin, transferrin, serum
ferritin and hepcidin were investigated. The comparison
group consisted of 19 pregnant women without
anaemia, as well as control group consisted of 15 non-
pregnant practically healthy women. The haemoglobin
concentration was measured by using “Mythic-18”
haematological auto analyzer. The serum transferrin level
was established by using an immunoturbidimetrymethod
with “Cormay” (Poland) reagent kits. The concentrations
of hepcidin and ferroportin were determined by using
“Cloud-Clone Corp.” (USA), and ferritin concentrations
were determined by using “Pishtaz teb” (Iran) reagents
through enzyme-linked immunosorbent assay (ELISA)
method. The study revealed a significant decrease in the
level of LF, ferritin, hepcidin and a significant increase in
ferroportin, transferrin level. A comprehensive definition
of various indicators of iron metabolism provides
important information not only for understanding the
pathogenesis of iron deficiency anaemia in pregnancy
but also for early diagnosis of the disease and the
appointment of the correct treatment.