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Pain Management 2019 & Internal Medicine 2019
International Journal of Anesthesiology & Pain Medicine
ISSN: 2471-982X
Page 79
JOINT EVENT
7
th
Edition of International Conference on
Pain Management
8
th
Edition of International Conference on
Internal Medicine &
Patient Care
&
March 25-26, 2019
Rome, Italy
Int J Anesth Pain Med 2019, Volume 5
DOI: 10.21767/2471-982X-C1-006
Prevalence of anemia before and after initiation of
antiretroviral therapy on HIV infected patients at Ras Desta
Damtew Memorial Hospital, Addis Ababa, Ethiopia
Chala Kenenisa Edae
Jimma University, Ethiopia
Objective:
The aim of this study is to determine the
prevalence of anemia before and after initiation of
antiretroviral therapy (ART) in HIV infected patients.
Method:
A retrospective study was conducted on HIV
infected patients before ART and was on follow up at the
ARTClinic of RasDestaDamtewMemorial Hospital Addis
Ababa, Ethiopia. Hemoglobin, Hematocrit, Red Cells and
Red Cell Indicesmeasurement and CD4+Tcell count was
measured using standard methodology at baseline and
after every 4 months of Three Visit antiretroviral therapy
(ART). Paired t-test was used to assessmean differences
for Hemoglobin, Hematocrit, Red Cell and CD4+ T cell
count before and after ART initiation.
Results:
Prevalence of anemia at baseline was 24.1 %(
261/1082). However, prevalence of anemia after ART
was significantly decreased in all three visits as follows;
first visit of ART was 11.98%(134/1118) (p < 0.05),after
second visit was 9.33%(91/975) (p < 0.05),after third visit
was 2.85%(23/805) ) (p < 0.05),The prevalence of anemia
was higher in females than in males at baseline (62.9%
vs. 37.1%) (P =0.00), and after first visit of ART (15.66%
vs. 5.76%) (P =0.00), after second visit was (9.61% vs.
8.83%), after third visit was (3.39% vs. 1.81%) (P=0.00).
Mean CD4+ T cell count of study subjects was 139cells/
µl ± 96.21(P<0.05) at baseline. The mean CD4+ T cell
count is significantly increased after ART in three visits
and found to be after the first visit of ARTwas 244cells/µl
± 135.4 (P<0.05), after the second visit was 294cells/µl ±
169.79 and after third visit 354cells/µl ±182.8 (p < 0.05).
Significance associationwas observed between Hgb, Hct
and CD4+ T cell count after ART.
Conclusions:
The prevalence of anemia based on the
hematological parameter (Hgb, HCT) decrease after
the initiation of ART except for RBC count. At the same
time, mean CD4 cell count significantly increased among
patients who started ART. This indicates that the use of
HAART in HIV/AIDS patients significantly increase CD4
count and decrease viral load along with decreasing
prevalence of anemia.
kchala@rocketmail.com