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Organic Chemistry 2018
Journal of Organic & Inorganic Chemistry
ISSN: 2472-1123
Page 25
August 16-17, 2018
Dublin, Ireland
6
th
Edition of International
Conference and Exhibition on
Organic Chemistry
T
he convergence of supramolecular chemistry and polymer
science especially porphyrin chemistry offers many powerful
approaches for building functional nanostructures with well-
defined dynamic behavior. The efficient metal-free three-component
reactions to synthesize 1,4,5-trisubstituted 1,2,3-porphyrin-triazoles
from available materials, such as porphyrin-aldehydes, nitroalkanes,
and organic azides, and also from porphyrin aldehydes, nitroalkanes,
and porphyrin azides is described. The process is enabled by an
organocatalyzed (morpholine:p-toluenesulfonicacid) Knoevenagel
condensation of the formyl group with the nitro compound, which is
followed by the 1,3-dipolar cycloaddition of the azide to the activated
alkene. The reaction features an excellent substrate scope, and
the products are obtained with good yield and regioselectivity. This
methodology was used for the synthesis of fused triazole heterocycles
from nitroporphyrin and organic azides.
Biography
Mian Gul Sayed completed his PhD from the University of Malakand, Dir
Lower Khyber Pakhtunkhwa, Pakistan. He did his research in the depart
ment of chemistry Ku Leuven University at Belgium under the supervision
of Professor Wim Dehaen. He is currently serving as an Assistant Professor
at the Institute of Chemical Sciences of University of Swat, Khyber Pakh-
tunkhwa, Pakistan.
mianguls696@uswat.edu.pkMetal free synthesis of beta-triazole tetra phenyl
porphyrins and related compounds
Mian Gul Sayed
University of Swat, Pakistan
Mian Gul Sayed, J Org Inorg Chem 2018, Volume 4
DOI: 10.21767/2472-1123-C4-011