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Organic Chemistry 2018 Journal of Organic & Inorganic Chemistry
ISSN: 2472-1123 Page 19
August 16-17, 2018
Dublin, Ireland
6th Edition of International
Conference and Exhibition on
Organic Chemistry
T he presentation will focus on a novel approach to
construction of physiologically active organic and
organometallic compounds based on computer-aided design,
new synthetic approaches and extensive biological screenings.
This study is focused on the design of hybrid compounds
possessing 2,6-dialkylphenol group with dual modes of action
– prooxidative activity and antioxidative activity. The presence
of metal atom allows extensive modification including
coordination to the targeted specific groups to control and tune
toxicity-activity profiles. The synthesis and biological activity
will be discussed. The anti/prooxidant activity has been studied
in vitro, ex vivo, in vivo experiments.
Biography
Elena R Milaeva pursued PhD at the A N Nesmeyanov Institute of Organo-
element Compounds of Russian Academy of Sciences in 1980. She is cur-
rently a Professor of organic chemistry, head of the department of medicinal
chemistry & fine organic synthesis at Lomonosov Moscow State University
respectively. Her research interests include: organic chemistry, medicinal
chemistry, organometallic chemistry.
Organic and organometallic derivatives of α-tocopherol
mimetics as promising antioxidants with dual functionality
Elena R Milaeva
Lomonosov Moscow State University, Russia
Elena R Milaeva, J Org Inorg Chem 2018, Volume 4
DOI: 10.21767/2472-1123-C4-011