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Nanobiotechnology 2018

Page 56

Nano Research & Applications

ISSN: 2471-9838

E u r o S c i C o n C o n f e r e n c e o n

Nanotech & Nanobiotechnology

J u l y 1 2 - 1 3 , 2 0 1 8

P a r i s , F r a n c e

N

anotechnology is attracting great attention worldwide in biomedicine. Targeted therapy based on drug nanocarrier systems

enhances the treatment of tumours and enables the development of targeted drug delivery systems. In recent years,

theranostics are emerging as the next generation of multifunctional nanomedicine to improve the therapeutic outcome of

cancer therapy. Polymeric nanoparticles with targeting moieties containing magnetic nanoparticles as theranostic agents have

considerable potential for the treatment of cancer. The use of directed enzyme prodrug therapy (DEPT) has been investigated

as a means to improve the tumour selectivity of therapeutics. Magnetic DEPT involves coupling the bioactive prodrug-activating

enzyme to magnetic nanoparticles that are then selectively delivered to the tumour by applying an external magnetic feld. Gene

therapy is an attractive method for meeting the needs for curing brain disorders, such as Alzheimer’s disease and Parkinson’s

disease. On the other hand, due to the fact that hepatocellular carcinoma (HCC) is resistant to standard chemotherapeutic agents,

gene therapy appears to be a more effective cure for HCC patients. Ultrasound-mediated drug delivery is a novel technique

for enhancing the penetration of drugs into diseased tissue beds noninvasively. This technique is broadly appealing, given the

potential of ultrasound to control drug delivery spatially and temporally in a non-invasive manner.

drhusseinammar@hotmail.com

Recent applications of nanotechnology in

advanced drug delivery systems

Hussein O Ammar

Future University, Egypt

Nano Res Appl 2018, Volume 4

DOI: 10.21767/2471-9838-C2-012