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Infectious Diseases 2018 Journal of Prevention and Infection Control
ISSN: 2471-9668 Page 68
June 07-08, 2018
London, UK
8th Edition of International Conference on
Infectious Diseases
Statement of the Problem: Infectious diseases are the most
significant public health challenges in Saudi Arabia. The concern
over such diseases has played a significant role in setting up
research funding priorities of pivotal institutions such as King
Abdulaziz City for Science andTechnology (KACST). Tuberculosis
(TB) is one of the primary challenges the Saudi healthcare
system faces and continues to be a public health challenge in
Saudi Arabia. The trends and outcomes of TB and multi-drug-
resistant tuberculosis (MDR-TB) in King Abdulaziz Medical City
hospital remain unaddressed. The purpose of this study is to
estimate mortality rate among TB cases and to identifying factors
associated with mortality.
Methodology & Theoretical Orientation: This is a retrospective
cohort study of 713 new TB cases at King Abdulaziz Medical City,
Riyadh diagnosed between January 1, 2000 and December 31,
2016. Patient charts, microbiology and virology lab databases
were used to retrieved data on demographic,
diagnosis, comorbidity, and mortality.
Findings: Of the 713 TB patients included in this study 110 died
giving an averagemortality rate of 22 per 1000 person-years (95%
CI: 18.2-26.4), elderly (≥ 60 years) had higher mortality rate of 36.5
per 1000 person-years (95% CI: 28.9-45.5). The adjusted hazard
of death was higher among males (adjusted hazard ratio (aHR):
1.901 [95%CI: 1.075-3.362, P = 0.027]), older patients (aHR: 1.019
[95%CI: 1.003-1.035, P = 0.021]), patients with lung disease (aHR:
3.853 [95%CI: 1.702-8.722, P = 0.001]), heart disease (aHR: 2.026
[95% CI: 1.089-3.772, P = 0.026]), cancer (aHR: 4.268 [95% CI:
2.268-8.032, P = 0.001]) and renal disease (aHR: 2.758 [95% CI:
1.529-4.976, P = 0.001]).
Conclusion & Significance: TB was associated with high
mortality rate, especially among males, elderly, and patients with
comorbidities, including: lung disease, heart disease, cancer, and
renal disease.
Tuberculosis outcomes at King Abdulaziz Medical City Hospital
Rawabi Aljadani1 and Anwar E Ahmed2
1King Abdulaziz Medical City, Saudi Arabia
2King Saud bin Abdulaziz University for Health Sciences, Saudi Arabia
J Prev Infect Cntrol 2018, Volume 4
DOI: 10.21767/2471-8084-C1-003