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academies
August 14-16, 2017 | Toronto, Canada
BRAIN DISORDERS AND DEMENTIA CARE
4
th
International Conference on
Neurosurg, an open access journal
ISSN: 2471-9633
R
ecently, we show that salivary β-amyloid protein (Aβ) can
be a potential biomarker to early diagnose Alzheimer’s
Disease (AD). At results, the quantity of Aβ40 and Aβ42 in
the saliva of normal young man (nYM) group, normal elderly
(nE) group and AD patients was measured in the range from
very low concentration (~ pg/ml) to high concentration (~ng/
ml). To find out another bio-marker in the saliva, using Maldi-
tof, we analyzed the size of the salivary protein below less
than 20 kDa. As a result, we found that there was a specific
protein which can distinguish the Np from the AD patients
and the size of that was about 15 kDa. In this study, we will
briefly introduce that the sequencing results for the salivary
protein which can distinguish between Np from the severe
AD patients. Therefore, we expect these results to further
increase the accuracy of the diagnosis of AD when the Aβ
level diagnosis was adapted simultaneously.
Speaker Biography
Ki-Bong Song has received his PhD degree in Physics, from the Department of Physics
of Sogang University, Korea. After working as a Post-doc in KIST (Korea Institute of
Science and Technology), he is now a Principal Researcher in ETRI (Electronics and
Telecommunications Research Institute), Korea. His main research includes diagnosing
technique in AD and development of wearable technology.
e:
kbsong
@etri.re.krSequencing of the saliva of normal person and AD patients
Ki-Bong Song
and
Yo-Han Choi
ETRI, Korea
Ki-Bong Song et al., Neurosurg 2017, 2:2
DOI: 10.21767/2471-9633-C1-006