nanobiotechnology-2018-scientifictracks

Nanobiotechnology 2018

Page 26

Nano Research & Applications

ISSN: 2471-9838

E u r o S c i C o n C o n f e r e n c e o n

Nanotech & Nanobiotechnology

J u l y 1 2 - 1 3 , 2 0 1 8

P a r i s , F r a n c e

harmaceutical formulations are a key for the effectiveness of therapeutic

agents. Nanotechnology provides a new direction to improve the solubility,

stability and bioavailability of various active agents. Incorporation of bioactive

molecules into nano-constructs improves their ability to safely cross biological

membranes such as the GI tract, BBB, and skin. Nanoparticles made of lipid

components, natural or synthetic polymers, carbon, metals and inorganic

materials, have been used as drug carriers. Recently, exosomes have been

used as natural carriers to direct drug loads to certain body sites. Nucleotide

and protein based biological drugs require suitable nano-delivery systems

that protect them from deterioration and direct them into specific cells and

organs. In addition to the delivery of drugs, nanoparticles have been used as

diagnostic agents and as carriers of combined diagnostic and therapeutic

agents. The various nano-delivery systems should be tailored to fit the route

of administration. The various nano-constructs that have been used for the

delivery of active agents and diagnostics by different routes of administration

will be discussed.

Biography

Abraham J Domb, is a Professor for Medicinal Chemistry and

Biopolymers at the Faculty ofMedicine of theHebrewUniversity,

Jerusalem. He earned Bachelor’s degrees in Chemistry,

Pharmaceutics and Law from Bar-Ilan and Hebrew University

and PhD degree in Chemistry from Hebrew University. He did

his Postdoctoral training at MIT/Harvard andwas R&DManager

at Nova Pharm. Co. Baltimore US from 1988-1992. Since 1992,

he is a Faculty member at the Hebrew University with interests

on Biopolymer synthesis and applications, Biodegradable

polymers, Drug delivery systems, Medicinal Chemistry and

Forensic sciences. During 2007-2012, he served as Head of the

Division of Identification and Forensic Sciences (DIFS), Israel

Police. Since April 2014, he is also President of the Jerusalem

College of Engineering.

Advances and challenges in pharmaceutical nanotechnology

Abraham J Domb

The Hebrew University of Jerusalem, Israel

Abraham J Domb, Nano Res Appl 2018, Volume 4

DOI: 10.21767/2471-9838-C2-011