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Medchem & Toxicology 2018

Page 80

Journal of Organic & Inorganic Chemistry

ISSN: 2472-1123

A n n u a l C o n g r e s s o n

Medicinal Chemistry,

Pharmacology and toxicology

J u l y 3 0 - 3 1 , 2 0 1 8

Am s t e r d a m , N e t h e r l a n d s

A

nethole is colorless fragrant; it resembles herb. This compound is likely to be viscous not completely soluble in water, which

makes it better suited for ethanol. Anethole is an unsaturated ether component, one aromatic benzene ring is connected

with unsaturated aliphatic carbon chains; that is used for its flavoring properties. It is 13 times sweeter than sugar. Today it can

be used in drinks to help make them more palatable and sweeter. It is also used in specific oral hygiene products, seasonings

and frozen berry products. Not only does the compound add a specific taste to items, but it also has incredibly helpful elements.

We have prepared this anethole from anisole reaction with propionyl chloride under Friedel Craft’s reaction. Later, ketone form

changed into hydroxyl in presence of NaBH4 and further dehydrogenated with KHSO4 to form isomer of anethole. This isomer

was separated from freezing method. The obtained trans-anethole was 99.98% (GC)

.

murliprabhas@gmail.com

Synthetic route of anethole

Murli Manohar

CSIR-CSMCRI, India

J Org Inorg Chem 2018, Volume 4

DOI: 10.21767/2472-1123-C3-009