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International Journal of Anesthesiology & Pain Medicine
ISSN: 2471-982X
Volume 4
March 26-28, 2018
Vienna, Austria
Pain Management 2018
Internal Medicine 2018
Page 41
JOINT EVENT
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E d i t i o n o f I n t e r n a t i o n a l C o n f e r e n c e o n
Internal Medicine and Patient Care
&
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E d i t i o n o f I n t e r n a t i o n a l C o n f e r e n c e o n
Pain Management
G
lobal consumption of antibiotics has increased nearly 40%
in the last decade. The incredible rapid antibiotic resistance
which is taking place worldwide is not only a serious threat to
the practice of modern medicine, but also a threat to global
public health. This issue of bacterial resistance is so alarming
that it caught the attention of G-20 Summit in both China (2016)
and Germany (2017), let alone the U.N. Assembly in 2016 had
called for a special meeting of “superbugs” which focused on the
escalating drug resistancewith respect to the sexually transmitted
disease gonorrhea and carbapenemresistant Enterobacteriaceae.
While the causes of antibiotic resistance are complex, certainly
human behavior play a significant role in the spread of antibiotic
resistant genes. In addition to the human behavior, the drivers
of resistance include agriculture sector, animal husbandry,
household and industry – these factors contribute significantly
to the spread of the resistant genes within the ecosystem. Such
resistant mechanisms are continuously emerging globally, which
threatens our ability to treat common infections, resulting in
increased death, disability and costs. Since the development
and clinical use of penicillin, nearly 1000 resistant-related beta-
lactamases that inactivate various types of antibiotics have been
identified. There is also a global concern about the emergence
of antibiotic resistant carried by the healthy individuals, the
commensal bacteria. The CDC and WHO surveillance data
shows that the resistance in E. coli is generally and consistently
the highest for antibacterial agents in both human and veterinary
medicine. Within communities, resistant bacteria circulate from
person to person or from animals and environment to person, or
vice versa. With 1 billion people travelling each year, bacteria is
becoming more mobile. The bacterial resistance can kill 700,000
worldwide each year and it’s been estimated to kill 10 million by
2050. TheWHO estimates 78million people a year get gonorrhea,
an STD that can infect the genitals, rectum and throat - there is a
widespread resistance to the first-line medicine ciprofloxacin as
well as increasing resistance to azithromycin. The emergence of
resistance to last-resort treatments known as extended-spectrum
cephalosporins (ESCs) is now eminent.
Biography
Nassir, R. (Keynote Address). Antibiotic Resistance: A Global Crisis. 2017
OMED International Seminar, October 7, 2017. Philadelphia, Pennsylvania,
USA. Departments of Pharmacology and Toxicology, and, Family and Com-
munity Medicine, Michigan State University, East Lansing, Michigan, USA.
Reza.Nassiri@hc.msu.eduAntibiotic resistance: a threat to modern
medicine
Reza Nassiri
Departments of Pharmacology and Toxicology, and, Family and Community
Medicine, Michigan State University, East Lansing, Michigan, USA.
Reza Nassiri, Int J Anesth Pain Med 2018, Volume 4
DOI: 10.21767/2471-982X-C1-001