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International Journal of Anesthesiology & Pain Medicine
ISSN: 2471-982X
Volume 4
March 26-28, 2018
Vienna, Austria
Pain Management 2018
Internal Medicine 2018
Page 40
JOINT EVENT
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E d i t i o n o f I n t e r n a t i o n a l C o n f e r e n c e o n
Internal Medicine and Patient Care
&
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E d i t i o n o f I n t e r n a t i o n a l C o n f e r e n c e o n
Pain Management
Biography
My research focuses on the genetic mechanisms and regulatory pathways in-
volved in pulmonary disease. In my graduate study I had focused on the role of
microRNAs and epigenetic regulators in disease pathology. Specifically, we had
identified alterations in gene regulation that correlates with clinical severity of
disease in IPF. This has allowed us to target potential therapies, some of which
have shown significant promise in our small animal models. While my current
focus is on patients with IPF, these pathways allow diverse application toomany
fields of study. We have developed several collaborations with clinicians and re-
searchers a like examining epigenetic regulation in diseases such as breast can-
cer, sepsis and acute respiratory distress syndrome. The central theme of my
research is to identify epigenetic mechanisms by which prolonged macrophage
survival can amplify the immune response and contribute to cancer, metastasis,
Autophagy, chronic lung inflammation in idiopathic pulmonary fibrosis (IPF) and
other inflammatory lung diseases.
duaa.dakhlallah@hsc.wvu.edu