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Journal of Clinical Immunology and Allergy
ISSN: 2471-304X
16 th EuroSciCon Conference on
Immunology
M a r c h 1 1 - 1 2 , 2 0 1 9
Am s t e r d a m , N e t h e r l a n d s
Immunology 2019
Background: The viruses (eg: rotavirus, astrovirus, and adenovirus) are
responsible for diarrhea in children, basically those are <5 years old. Detection
of the entire virus is crucially important to the development of the effective
cure. This study aimed to determine the prevalence of common viruses
in children with <5 years old presented with diarrhea to the Lala Lajpat Rai
Memorial Medical College (LLRM) centre(Meerut) North India, India.
Methods: Total 312 fecal samples were collected from diarrheal children
(duration 3 years: in year 2014 (n=118), 2015 (n=128) and 2016 (n=66)) of <5
years of age who presented with acute diarrhea at the Lala Lajpat Rai Memorial
Medical College (LLRM) centre(Meerut) North India, India. All samples were
analyzed for the presence of rotaviruses, adenovirus and astrovirus using EIA/
RT-PCR.
Results: In 312 samples from children with acute diarrhea, viral agent was
found rotavirus A was the most frequent virus identified (57 cases; 18.2%),
followed by astrovirus in 28 cases (8.9%), adenovirus in 21 cases (6.7%).
Mixed infections were found in 14 cases, all of which presented with acute
diarrhea (4.48%).
Conclusions: These viruses are a major cause of diarrhea in children <5 years
old in North India. Rotavirus A is the most common etiological agent, followed
by astrovirus. This surveillance is important to vaccine development of the
entire population.
Biography
Ali ilter Akdag is pursuing his PhD at Jamia Hamdard University
since three years. His research area is Molecular Virology and
Vaccinology. He works on acute gastroenteritis viruses, like
rotavirus, adenovirus, astrovirus, norovirus, and sapovirus. He
has completed MSc in Zoology (2013-2015) from Osmania
University in Hyderabad, India. He won many certificates and
awards. He has actively participated national and international
conferences.
Molecular detection of acute virus infection in children
hospitalized with diarrhea in North India during 2014-2016
Ali ilter Akdag and Pratima ray
Jamia Hamdard University, India
Ali ilter Akdag et al., J Clin Immunol Allergy 2019, Volume:5
DOI: 10.21767/2471-304X-C1-008