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Environmental Science & Technology 2018 Journal of Environmental Research
Page 30
March 29-31, 2018
Vienna, Austria
4th Edition of International Conference on
Environmental Science
& Technology 2018
Objectives: Themain objective of this study is to explore the effect
of ambient particulate matter (PM2.5) exposure on hypertension.
Methods: In this study, we investigated the blood pressure of
1,998,795 participants and their individual PM2.5 exposure values
in China from 2014 to 2015 from National Free Pre-pregnancy
Check-ups Project and the Ministry of Environmental Protection
of the People’s Republic of China. In this research, the PM2.5
exposure time was divided into five periods (3 days before survey,
1 week before survey, 1month before survey and 2months before
survey as well as 3 months before survey). We calculated the
average concentration and the corresponding quartiles of PM2.5
in these five periods. We used logistic regression to explore the
association between PM2.5 exposure and hypertension in different
periods, and compared the effects of different quartiles of levels
of PM2.5 exposure on hypertension in each exposure phase. The
effects were adjusted for age, body-mass index (BMI), education
level, second-hand smoking and drinking.
Results: A total of 1,998,795 participants were included, among
which 89,255 (4.5%) were hypertension. Each 10 μg/m³ increase
of PM2.5 was associated with increases in the risk of hypertension
of 9.56% (95% CI 9.29-9.83) in the period of 3 days before survey,
15.68% (95% CI 15.33-16.02) in the period of 1 week before
survey, 27.22% (95% CI 26.71-27.72) in the period of 1 month
before survey, 16.54% (95% CI 16.13-16.96) in the period of 2
months before survey, and 7.75% (95% CI 7.40-8.10) in the period
of 3 months before survey. We found that PM2.5 exposure during
1 month before survey had the highest significant increase in the
risk of hypertension, and we then explored the dose association
between hypertension and PM2.5 exposure based on quartiles.
Compared with the lowest quartile of PM2.5 exposure, the second,
third and fourth quartile all increased the risk of hypertension, and
fourth quartile PM2.5 exposure during 1 month before survey was
the most obvious increased, and the odds ratio was 1.674 (95%
CI 1.643-1.706)
Conclusion: We observed that ambient PM 2.5 exposure played
an important role in human health and could increase the risk of
hypertension.
Recent Publications
1. Guo T, Wang Y, Zhang H, Zhang Y, Zhao J, Wang Y et al.
(2017) The association between ambient temperature
and the risk of preterm birth in China. Science of the
Total Environment 613-614:439-446.
Biography
Guo Tongjun, a master candidate majoring in Epidemiology and Health Sta-
tistics in the National Research Institute for Family Planning, Peking Union
Medical College, China. He focus in the data analysis of reproductive health,
having strong interest in the relationship between environment and health.
He has published an article entitled “The association between ambient tem-
perature and the risk of preterm birth in China” in the science of the environ-
ment journal.
The association between ambient PM2.5 exposure and the risk
of hypertension in China: A retrospective cohort study
Tongjun Guo1, 2, Yuanyuan Wang1, 2, Jun Zhao1, Ya Zhang1, Hongguang Zhang1,
Zuoqi Peng1 and Xu Ma 1
1National Human Genetic Resources Centre, China
2Peking Union Medical College, China
Tongjun Guo et al., J Environ Res, Volume 2