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Dentistry and Craniofacial Research
ISSN: 2576-392X
3 rd Euroscicon Conference on
M a r c h 2 5 - 2 6 , 2 0 1 9
B u d a p e s t , H u n g a r y
Dental Hygiene 2019
Dental & Dental Hygiene
Monika Dybicz, Dent Craniofac Res 2019, Volume:4
DOI: 10.21767/2576-392X-C2-018
Trichomonas tenax, cosmopolitan flagellate inhabiting human oral cavity,
is the etiological agent of oral trichomonosis associated with gingival and
periodontium deterioration. The protozoan was also detected in lymph nodes,
submaxillary glands, tonsils, bronchi, lungs, mammary gland and liver. Most
of the patients with less frequent location of the trichomonad infection had
decreased immunity due to chronic diseases and transplant surgery. The
occurrence of T. tenax in the oral cavity of patients with systemic disorders,
genetic diseases, HIV/AIDS, rheumatoid arthritis, and renal transplant has been
described. The aim of the study was to investigate the prevalence of infection
with Trichomonas tenax identified by molecular techniques amplifying the
region of ITS1-5.8S rRNA-ITS2 specific for T. tenax. The study included 498
persons: 261 women and 157 men aged from 6 to 82 years categorized into
four groups: diabetic, renal transplant, rheumatoid arthritis patients and the
control group. Higher T. tenax incidence in all studied patients was revealed
in comparison with generally healthy patients of control group with a proper
immune system (12.0-14.1%, and 10.2%, respectively). However, these
prevalence differences are not very significant; similar results were obtained
in other studies conducted on similar groups of patients, as well as in other
diseases. Comparative assessment of results in our study indicated that the
frequency of infection with T. tenax differ depending on the human age, with
the higher prevalence of it in adults; no trichomonads were found in persons
under 32 years of age. All infected with T. tenax showed symptoms of gingival
and periodontium deteriorations. Simultaneously, renal transplantation,
diabetes, rheumatoid arthritis and related therapy do not affect T. tenax
incidences and no increased risk of the infection has been observed in the
patients; the permanent medication used due to main disease should be taken
into consideration as likely inhibitory factor.
Biography
Monika Dybicz has completed her PhD at the age of 28 years
at Medical University of Warsaw, Poland. She is an assistant
of professor at the Department of General Biology and
Parasitology (Medical University of Warsaw, Poland). She has
published more than 35 papers in scientific journals.
MOLECULAR STUDIES ON INFECTION WITH TRICHOMONAS TENAX IN
RESPECT TO ORAL HEALTH OF PATIENTS WITH VARIOUS SYSTEMIC
DISEASE REQUIRING IMMUNOSUPPRESSIVE THERAPY
Monika Dybicz
Medical University of Warsaw, Poland