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Chemistry Education 2018
Journal of Organic & Inorganic Chemistry
ISSN: 2472-1123
Page 71
August 27-28, 2018
Zurich, Switzerland
8
th
Edition of International Conference on
Chemistry Education
and Research
B
oswellia dalzielii (B. dalzielii)
Hutch. is from the genus
Boswellia and the family of Burseraceae. It is a tree plant
abundantly found in North-Western Nigeria and very common
among the locals as a potent source of ethnomedicine. This work
aimsat evaluating thephytochemical, antioxidant, antiproliferative
and antifungal activities of the stem bark of Boswellia dalzielii.
The phytochemical screening of the stem bark of B. dalzielii
indicated the presence of tannins, saponins, flavonoids, steroids,
carbohydrate. The phenolic content was found to be highest in
sub-fraction C (481.20±10.13 mg GAE/g) and flavonoid contents
were found to be highest in methanolic extract (142.17±4.82 mg
RE/g). Boswellia dalzielii stem bark extracts, fractions and sub-
fractionsB, CandDexhibited antioxidant capacity; and the highest
antioxidant activities were recorded from aqueous fraction and
methanol extract for the DPPH; and aqueous fraction and sub-
fraction D for the FRAP assay. Antiproliferative, sub-fractions
C and D at the concentration of 125 µg/ml gave the highest
percentage of inhibition (90%) followed by sub-fraction B (50%)
at 250 µg/ml. The antifungal screening of the bark methanolic
extract, fractions and sub-fractions showed activity against
Candida albicans; ethyl acetate and aqueous fractions showed
activity against Penicillium notatum, while there was no activity
shown by methanolic extract, fractions and sub-fractions against
Aspergillus niger
. These results further showed that the stem
bark of
Boswellia dalzielii
has high growth inhibitory activity on
the seeds of
Guinea corn
; and therefore may possess anticancer
component(s) which need(s) further investigation.
kafutisungu@gmail.comPhytochemical studies and
in vitro
antioxidant,
antiproliferative and antifungal activities of the stem bark of
Boswellia dalzielii
Hutch.
Yves S Kafuti
1
and
Kalulu M Taba
2
1
University of Kinshasa, DR Congo
J Org Inorg Chem 2018, Volume 4
DOI: 10.21767/2472-1123-C5-015