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Page 76
Volume 4
December 10-12, 2018
Rome, Italy
Nano Research & Applications
ISSN: 2471-9838
Advanced Materials 2018
Nano Engineering 2018
JOINT EVENT
22
nd
International Conference on
Advanced Materials
and Simulation
&
22
nd
Edition of International Conference on
Nano Engineering &
Technology
S
ynergy between physics, material sciences and biotechnology
during last decade has led to a tremendous scientific progress
in the fields of bio detection and nanomedicine. This tight
interaction led to the emergence of a new class of bioinspired
systems that enables to bring the area of biosensorics e.g., for
cell or molecular diagnostics and analytics to the new level. The
advances are expected in terms of possibility for early diagnostics
of diseases due to the increased sensitivity of the detectors; real
time and high through put analysis offered by combination of
integrated electronics andmicrofluidic approach and establishing
the new functional formats for the bioassays. Most promising
candidates for the future diagnostics are the electronic nano
biosensors that have attracted great attention in the last decades
since they provide rich quantitative information for medical and
biotechnological assays without pre-treatment and specific
optical labelling of the detected species. One dimensional nano
structures in particular semiconductor and metallic nano wires
have attracted attention as highly efficient sensor elements
due to their high surface-to-volume ratio, which simplifies the
detection of biochemical species down to single molecules. The
simultaneous detection of multiple targets within a single chip on
a point of care device is amilestone drawing great attentionwithin
bio and nanotechnology areas for more than a decade. Here, we
demonstrate a multiplexed, label free and real time detection
platform for small molecules like hormones, DNA sequence or
pathogenic proteins. The nanowires based devices offer noise
reduced, versatile and reliable electrical characteristics with high
on/off ratios upto 106. A sensitive and selective binding of the
targets onto the SiNW-FETs can be realized by using aptamers/
antibodies, etc., as receptors in order to allow high sensitive
screenings in physiological conditions.
g.cuniberti@tu-dresden.deGianaurelio Cuniberti
1, 2, 3, 4
and
Stephanie Klinghammer
1
Bergoi Ibarlucea
1, 2, 3
Lot-
ta Roemhildt
1
Felix Zoergiebel
1, 2, 3
Sebastian Pregl
1, 2, 3
and
Larysa Baraban
1, 2, 3
1
Max Bergmann Center of Biomaterials Dresden, Germany
2
Institute for Materials Science Tu Dresden, Germany
3
Center for Advanced Electronics Dresden, Germany
4
Dresden Center for Computational Materials Science (DCMS), Germany
Nano Res Appl 2018, Volume 4
DOI: 10.21767/2471-9838-C7-028
Lab on a wire: application of silicon
nanowires for nanoscience and
biotechnology