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Vascular Surgery 2019
Journal of Vascular and Endovascular Therapy
ISSN: 2573-4482
Page 62
March 28-29, 2019
Rome, Italy
Vascular Surgery
4
th
Edition of World Congress & Exhibition on
Nguyen Dang Dinh Thi, J Vasc Endovasc Therapy 2019, Volume 4
DOI: 10.21767/2573-4482-C1-006
Left ventricular non-compaction cardiomyopathy: a case
follow up with medical treatment
Nguyen Dang Dinh Thi
Khanh Hoa general hospital, Vietnam
A
t birth, heart failure is caused by fetal cardiomyopathy
or extracardiac conditions (such as sepsis,
hypoglycemia, and hypocalcaemia). Left ventricular
non-compaction cardiomyopathy (LVNC) is a genetic
cardiomyopathy characterized by prominent ventricular
trabeculations and deep intertrabecular recesses, or
sinusoids, in communication with the left ventricular
cavity. The clinical sequelae of these deformities are the
syndrome of heart failure and the risk for arrhythmias
and stroke. In many decades, with only morphological
assessment available and no definitive genetic
pathway, LVNC remains a diagnostic and management
challenge. In this case, we presented an eleven-month-
old girl diagnosed with LVNC at two-month-old based on
prominent trabeculations and intertrabecular recesses
on a visualized estimate on echocardiography. We
have used the Jenni criteria to evaluate the presence
of ofher LVNC. In Vietnam, we are lack of experience in
CMR and cardiac CT in children and the genetic testing
is not available as well. Her clinical present with Ross
modified classification in stage III. In medical therapy
we have used Captopril oral 0.6 mg/kg q8h every day;
Digoxin oral 10 μg/kg/d and Spironolactone oral 1.5 mg/
kg q12h intermittency depending on clinical present.
Bottle feeding with breast milk in the first six months
and with powder milk, rice soup, seafood, fruits (oranges
especially), multivitamins, Vitamin D3 and etc., since
seven-month-old. At 11-month-old, her EF has improved
from 33% to 43%, still malnutrition with 7 kg in weight,
fatigue, shortness of breath, tachypnea and difficulty in
feeding. In this case, wewish tomake for amore accurate
diagnosis and find a management approach with special
attention to guidance for treatment in heart failure due to
LVNC.
Recent Publications
1. Bennett C E and Freudenberger R (2016)
The current approach to diagnosis and
management of left ventricular noncompaction
cardiomyopathy: reviewof the literature. Cardiol
Res Pract 5172308.
2. Fujino M, Tsuda E, Hirono K, et al. (2018) The
TNNI3 Arg192His mutation in a 13-year-old girl
with left ventricular noncompaction. J Cardiol
Cases 18(1):33-36.
3. Masarone D, Valente F, Rubino M, et al. (2017)
Pediatric heart failure: a practical guide to
diagnosis and management. Pediatr Neonatol
58(4):303-312.
4. Ying Nan Lin, Yu Qiang Wang, Yi Yu, et al.
(2014) Left ventricular noncompaction
cardiomyopathy: a case report and literature
review. Int J Clin Exp Med 7(12):5130-5133.
5. Jenni R, Oechslin E, Schneider J, Attenhofer
C, et al. (2001) Echocardiographic and
pathoanatomical characteristics of isolated
leſt ventricular non-compaction: a step towards
classification as a distinct cardiomyopathy.