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May 24-25, 2018
London, UK
Vascular Surgery 2018
3
rd
Edition of World Congress & Exhibition on
Vascular Surgery
Journal of Vascular and Endovascular Therapy
ISSN: 2573-4482
Aim:
We aimed to evaluate short and mid-term results of
commercially available prefabricated vascular grafts made
of bovine pericardium. Herein, we report on our institutional
experience with the use of these grafts.
Methods:
Six patients underwent Aorto- Iliac repair with
commercially available graftsmade of bovine pericardium (BPG),
in an additional patient a BPG was utilized for the management
of an infected PTFE fem-pop bypass graft, for the management
of graft infection or in the presence of systemic infection.
Comorbidities, procedure related details, postoperative mortality
and mid-term follow up were assessed and analyzed. The seven
patients treated with BPGs form the base of this study.
Results:
71% (5) were male, mean age was 61.4±10.9 years.
Comorbidities: arterial hypertension 100% (7), smoking 71% (5),
coronary artery disease 43% (3), peripheral arterial disease 86%
(6) and chronic renal disease 29% (2). Indications for surgery
were: i) graft infection 71% (5), ii) arterial reconstruction in the
presence of systemic infection 29% (2). Five patients (71%) had
a history of previous vascular surgery. In 86%, polymicrobial
cultures were available (6), amongst the isolated pathogens
were Staph aureus, Pseudomonas aeruginosa and E. coli. For
direct repair a bifurcated graft configuration was used in all
aortic cases. Median follow-up: 107 days (max: seven months).
Thirty-day mortality was 14% (1) – congestive heart failure – a
patient operated successfully for an infected graft, undergoing
surgery for control of infection prior to intended cardiac surgery,
overall mortality was 14%.
Conclusion:
Our data support the conclusion that the use of
BPGs represents an excellent conduit for the management of:
i) aortic graft infections, ii) aortic reconstruction in the presence
of systemic infection, and iii) infected prosthetic grafts utilized
in peripheral arterial reconstructive surgery.
Recent Publications
1. Piechota Polanczyk A, Demyanets S, Mittlboeck M,
Hofmann M, Domenig C M, Neumayer C, Wojta J, Klinger
M, Nanobachvili J and Huk I (2015) The influence of
simvastatin on NGAL, matrix metalloproteinases and
their tissue inhibitors in human intraluminal thrombus
andabdominal aortic aneurysmtissue. EuropeanJournal
of Vascular and Endovascular Surgery 49(5):549-55.
2. Fokkema M, Vrijenhoek J E, Den Ruijter H M, Groenwold
R H, Schermerhorn M L, Bots M L, Pasterkamp G, Moll
F L and De Borst G J; TREAT CARE study group (2015)
Stenting versus endarterectomy for restenosis following
prior ipsilateral carotid endarterectomy: an individual
patient data meta-analysis. Ann Surg. 261(3):598-604.
3. Domenig C Linni K, Mader N, Kretschmer G,
Magometschnigg H and Hölzenbein T J (2008)
Subclavian to carotid artery transposition: medial
versus lateral approach. European Journal of Vascular
and Endovascular Surgery 35(5):551-7.
4. Kinstner C, Teufelsbauer H, Neumayer C, Domenig
C, Wressnegger A, Wolf F and Funovics M (2014)
Endovascular repair of thoracoabdominal aortic
aneurysms with a novel multibranch stent-graft design:
preliminary experience. Journal of Vascular Surgery
(Torino) 55(4):543-50.
5. PiechotaPolanczykA,GoracaA,DemyanetsS,Mittlboeck
M, Domenig C, Neumayer C, Wojta J, Nanobachvili J,
Huk I and Klinger M (2012) Simvastatin decreases
free radicals formation in the human abdominal aortic
aneurysm wall via NF-κB. European Journal of Vascular
and Endovascular Surgery 44(2):133-7
Biography
Ihor Huk is the Chairman of Division of Vascular Surgery since 2013 and
Director of Vascular Laboratory since 1994, Department of Surgery Medical
Bovine pericardial grafts for the management of aortic graft
infections: single center experience
Ihor Huk, Christoph M Domenig, Markus Klinger, Christopher Burghuber, Wolf
Eilenberg, Christoph Neumayer
and
Josif Nanobachvili
Medical University of Vienna, Austria
Ihor Huk et al., J Vasc Endovasc Therapy 2018, Volume 3
DOI: 10.21767/2573-4482-C1-002