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American Journal of Ethnomedicine
ISSN: 2348-9502
April 16-17, 2018
Amsterdam, Netherlands
Pharmacognosy 2018
Page 17
6th Edition of International Conference on
Pharmacognosy and
Medicinal Plants
Coral reefs extend as deep as 150 meters and with the
development of new technologies to go deeper, scientists
are beginning to explore ‘Mesophotic Coral Ecosystems’ (MCEs)
existing in low light levels, which still allows for photosynthesis.
Mesophotic coral ecosystems (MCEs) are almost entirely
unexplored; they are a treasure-trove for discovering new
species and their associated bioactive chemical compounds.
Organisms such as soft corals, sponges, and microbes living
on coral reefs naturally produce potent cocktails of chemicals
to defend themselves from competitors and harmful predators.
EU-funded Horizon 2020 project TASCMAR, which aims to
tackle major bottlenecks in the discovery, development, and
commercialization of marine-derived chemical compounds with
a specific focus on using new biological and chemical resources
from MCEs. The project partners are working on developing
innovative technologies for the sustainable cultivation of marine
resources, e.g. through the isolation of chemicals in their natural
environment without the need to harvest them. The project is
specifically looking for new chemical compounds active against
age-related illnesses such as Alzheimer’s, Parkinson’s, cancer,
and aging diseases related to muscles and skin.
Recent Publications
1. Leman-Loubière C, Le Goff G, Retailleau P, Debitus C and
Ouazzani J (2017) Sporothriolide-related compounds
from the fungus hypoxylon monticulosum CLL-205
isolated from a Sphaerocladina sponge from the Tahiti
Coast. J. Nat .Prod. 80(10):2850–2854.
2. Gallego A, Meton I, Baanante I V, Ouazzani J, Adelin E, et
al. (2017) Viability-reducing activity of Coryllus avellana L.
extracts against human cancer cell lines. Biomedicine &
Pharmacotherapy 89:565–572.
3. Le Goff G, Adelin E, Arcile G and Ouazzani J (2017) Total
synthesis of the antibiotic 4-hydroxycyclopent-2-en-1-
one acrylate derivative EA-2801. Tetrahedron Letters
58:2337–2339.
4. Adelin E, Le Goff G, Retailleau P, Bonfill M and Ouazzani
J (2017) Isolation of the antibiotic methyl (R,E)-3-(1-
hydroxy-4-oxocyclopent-2-en-1-yl)-acrylate EA-2801 from
trichoderma atroviridae. J. Antibiotics 70(11):1053–1056.
5. Ouazzani J, Benayahu Y and Trougakos I (2016) Seeking
the fountain of youth in the twilight zone. The Marine
Biologist 7:9−11.
Biography
Jamal Ouazzani completed his PhD in AppliedMicrobiology in 1988 fromParis
XI University-France and obtained a research position at the National Center
for Scientific Research (CNRS) in 1989 ). Since 2014, he has held
the position of CNRS Research Director within the Institute for Chemistry of
Natural Compounds (ICSN, and leads the ICSN Pilot-Unit
. He has an interdisciplinary profile covering fundamental
and applied microbiology, natural product chemistry, biochemistry, biocataly-
sis, bioremediation, innovative biotechnology design, building and implementa-
tion. He has been engaged in diverse consulting activities since 1996, for envi-
ronmental, cosmetic and pharmaceutical companies. He has published more
than 62 publications in peer-reviewed journals and has obtained nine patents.
He collaborates with various companies in the field of ethno-pharmacology,
bioactive natural compounds from plants, marine organisms and microorgan-
isms, innovative extraction and bio-resource cultivation technologies.
TASCMAR EU project—marine invertebrates
and associated-microorganisms, a global
science for a global valorization
Jamal Ouazzani
Institut de Chimie des Substances Naturelles, France
Jamal Ouazzani, Am J Ethnomed 2018, Volume 5
DOI: 10.21767/2348-9502-C1-004