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Volume 4
Journal of Pediatric Care
ISSN: 2471-805X
Page 44
JOINT EVENT
Pediatric Critical Care 2018 &
World Pediatrics 2018
October 18- 20 , 2018
October 18- 20, 2018 Warsaw, Poland
&
6
th
International Conference on
25
th
World Pediatrics Conference
Pediatric Critical Care and Emergency Medicine
Necrotizing enterocolitis in a preterm infant newborn and role of feeding - an update!
Amr Ismael M Hawal
Prime Healthcare Group, UAE
I
t is a clinical case presentation of a male preterm infant newborn (+31 weeks) that was delivered in our hospital and
transferred to NICU because of prematurity, VLBW and need of respiratory support. Baby shortly underwent necrotizing
enterocolitis (NEC) on fifth day of life shortly after starting of expressed milk feeding. It was early detected by the use of
near infrared abdominal spectroscopy (NIRS). Baby was deteriorated clinically in a couple of hours and undergone intestinal
perforation with peritonitis. So, abdominal exploration surgery with intestinal resection and end to end anastomosis was done
urgently. Baby improved gradually and early feedings was started and gradually increased up to full feedings with the use of
human fortified milk (HMF), probiotics and prebiotics. The study stated the evidence-based feeding strategy guidelines for
necrotizing enterocolitis (NEC) among very low birth weight infants and role of trophic feedings, probiotics, prebiotics and
micronutrients in prophylaxis, prevention and management of NEC. Prematurity is the single greatest risk factor for NEC and
avoidance of premature birth is the best way to prevent NEC; the role of feeding in the pathogenesis of NEC is uncertain, but
it seems prudent to use breast milk (when available) and advance feedings slowly and cautiously; NEC is one of the leading
causes of mortality, and the most common reason for emergent GI surgery in newborns; NEC remains a major unsolved
medical challenge, for which no specific therapy exists, and its pathogenesis remains controversial; a better understanding of
the pathophysiology will offer new and innovative therapeutic approaches, and future studies should be focused on the roles
of the epithelial barrier, innate immunity, and microbiota in this disorder; and bioinformatics modeling is a new emerging
strategy aimed at understanding the dynamics of various inflammatory markers and their application in early diagnosis and
treatment.
amr106@gmail.comJ Pediatr Care 2018, Volume 4
DOI: 10.21767/2471-805X-C4-015