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Journal of Organic & Inorganic Chemistry
ISSN: 2472-1123
August 16-17, 2018
Dublin, Ireland
Organic Chemistry 2018
Page 15
6th Edition of International
Conference and Exhibition on
Organic Chemistry
Environmentally benign, operationally simple, and robust
reactions,particularlythoseemployingreusablesolidcatalysts
and water as a solvent, are of significant interest to the chemical
industry. Here, heterogeneous palladium catalysts supported on
ordered mesoporous carbonaceous nanocomposites including
carbon-silica, CoO-C and quaternary ammonium phase transfer
agent modified mesoporous carbonaceous resins, were applied
to the water-mediated C-C bonds formation. The mesoporous
Pd/CoO-C catalyst showed a high yield of biphenyl (49%) in
the water-mediated Suzuki coupling reaction of chlorobenzene
and phenylboronic acid. Product yields in the reaction of aryl
chlorides containing electron-withdrawing groups attached to
their benzene ring can reach approximately 90%. Very small Pd
clusters consisting of approximately 3 atoms and Pd-O bonds
formed on the interface between CoO and Pd nanoparticles.
The unsaturated coordinative Pd may be responsible for the
activation of chlorobenzene in the absence of any additives
or ligands. A nitrogen-containing functional group modified
and ordered mesoporous resin material was also used to
support a reusable solid Pd catalyst. The grafted quaternary
N coordination with highly dispersed Pd NPs creates an
electronically rich environment for surface atoms and causes
a distinct enhancement in the stabilization and accessibility
of these particles to organic substances in aqueous solution.
The mesoporous Pd catalysts are active in the C-2 arylation of
N-methylindole when water is used as the solvent without any
other additive or the exclusion of air. The catalysis likely occurs
on the Pd surface rather than in solution. thiol-functionalized
mesoporous silica, which can trap soluble Pd species, was
used to confirm the negligible leaching in solution and therefore
heterogeneous reaction. These heterogeneous catalyst are
stable, showing unobvious activity loss after ten catalytic runs.
Additionally, uniform mesopores and the hydrophobic nature of
the carbon support may also facilitate the mass transfer of the
reactant molecules and enrichment inside pores.
Recent Publications
1. L Djakovitch and F X Felpin (2014) Chem. Cat. Chem.
6(8):2175-20187.
2. L L Duan et al. (2016) An efficient reusablemesoporous
solid based Pd catalyst for selective C2 arylation of
indoles in water. ACS Catal. 6(2):1062-1074.
Biography
Ying Wan received her PhD Degree in Industrial Catalysis from the East
China University of Science and Technology in 2002. She is a Professor
of Chemistry in Shanghai Normal University, P R China. She joined the uni-
versity and was promoted to a Full Professor in 2006. She is currently the
Leader of the Program for Innovative Research Team at the same univer-
sity, China. She has contributed to about 70 peer-reviewed scientific publi-
cations withmore than 7000-times citations and 3 books. She has been an
Associate Editor of Journal of Porous Materials since 2013. Her research
interests include: sintering and poisoning-resistance metal nanocatalyst
supported onmesoporous carbons, and their applications in green organic
synthesis and energy chemistry.
Reusable mesoporous solid-based Pd
catalysts for C-C bond formation in water
Ying Wan
Shanghai Normal University, P R China
Ying Wan, J Org Inorg Chem 2018, Volume 4
DOI: 10.21767/2472-1123-C4-010