14 / 27
NanoMat 2018
Nano Research & Applications
ISSN: 2471-9838
Page 81
April 26-27, 2018
Rome, Italy
17
th
Edition of International Conference on
Emerging Trends in
Materials Science and
Nanotechnology
Nano Res Appl, Volume:4
DOI: 10.21767/2471-9838-C1-009
T
his paper introduces a novel approach to fabricate bio-
scaffolds by using composite materials of 3D printed PLA
and electro-spun PCL nanofibers. Polycaprolactone (PCL) is
biodegradable polyester with a low melting point and it is one of
the most common biodegradable materials in long-term implants
and controlled drug release applications. Polylactic acid (PLA) is
another biodegradable polymer in use for medical applications.
PLA is a biodegradable and bioactive thermoplastic derived from
renewable resources such as corn starch or sugarcane. PLA
has five times higher tensile strength than PCL which provides
better mechanical stability for the bio-scaffold applications.
By combining the excellent bio-solvability of PCL and good
mechanical stability of PLA, a novel composite bio-scaffold
was fabricated. For the higher cell adhesion or growth, PCL was
formed as nanofibers by electro spinning technology while PLA
was formed as a meshed matrix for higher mechanical strength.
The PCL fibers fabricated by electrospinning technology ranged
between 100s of nanometers and 10s of micrometers depending
on concentration of solvents, applied voltage, flow rate and etc.
ThePLAmeshwas fabricatedbyastateof theart fuseddeposition
modeling (FDM) type 3D printer with 0.2 mm thickness. In results,
the fabricated bio-scaffolds showed higher strength compared to
a single PCL material and higher cell adhesion environment.
hwchoi@kmu.ac.krFabrication of composite bio-scaffolds by using 3D printed PLA
and electrospun PCL nanofibers
Hae Woon Choi, Jae Hoon Choi, Ji Soo Kim
and
Min Ji Sohn
Keimyung University, South Korea