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NanoMat 2018
Nano Research & Applications
ISSN: 2471-9838
Page 87
April 26-27, 2018
Rome, Italy
17
th
Edition of International Conference on
Emerging Trends in
Materials Science and
Nanotechnology
A
dvanced nanobiomedical applications have been traditionally
based on chemically synthesized, bottom-up, multifunctional
core/shell or Janus-type inorganic nanoparticles. Herewe present
a novel type of structure especially suited for diverse biomedical
uses: magnetoplasmonic nanodomes. The nanodomes are
composed of a combinedmagnetic and plasmonic hemispherical
shell deposited onto 100 nm diameter polystyrene beads. The
variation of the materials and their thicknesses in the shell
enables tuning both the optical and magnetic properties of the
nanostructures. For example, Fe magnetic layers lead to in-plane
magnetization, while [Co/Au] multilayers result in structures with
out-of-plane magnetic anisotropy. Using Au plasmonic layers
allows adjusting the plasmonic resonance to be in the near
infrared, where the penetration in tissues is maximized. The very
high plasmonic absorption of the nanodomes is used for very
efficient local optical heating, i.e., photo-hyperthermia for cancer
treatment. The magnetic character of the nanodomes allows
to remotely manipulate them and thus to easily regulate the
level of photo-hyperthermia. Moreover, given their asymmetric
shape the nanodomes exhibit a strong optical anisotropy, where
the plasmonic resonances parallel and perpendicular to the
nanodomes take place at different wave lengths. Moreover,
since the nanodomes have magnetic anisotropies, when using
alternating magnetic fields they can rotate inside liquids. This
rotation can be easily tracked optically using the different
absorption of the nanodomes depending on their orientation
with respect to the light polarization. Since the rotation of the
nanoparticles depends strongly on the viscosity of the medium,
which in turn depends on the temperature, the optical tracking
of the rotation can be used to accurately determine the local
temperature around the nanodomes, i.e., nanothermometry.
Thus, combining the nanodomes efficient photo-hyperthermia
with their nanothermometry capabilities, allows in-situ tracking
the efficiency of photo-hyperthermia treatments.
Josep.Nogues@icn2.catMagnetoplasmonic nanodomes as a novel structure for
biomedical applications
J Nogués
1, 2
, Z Li
2
, P Güell-Grau
2
, J L Tajada
2
, A López-Ortega
3
, P Vavasori
3
and
A Aranda-Ramos
4
1
ICREA, Spain
2
Catalan Institute of Nanoscience and Nanotechnology, Spain
3
CIC nanoGUNE, Spain
4
Universitat Autònoma de Barcelona, Spain
Nano Res Appl, Volume:4
DOI: 10.21767/2471-9838-C1-009