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A n n u a l C o n g r e s s o n
Medicinal Chemistry,
Pharmacology and toxicology
Journal of Organic & Inorganic Chemistry
ISSN: 2472-1123
J u l y 3 0 - 3 1 , 2 0 1 8
Am s t e r d a m , N e t h e r l a n d s
Medchem & Toxicology 2018
Page 18
I
n the last decades, organic peroxides have received considerable attention from
chemists and drug design experts, which is associated with a need in the search
for drugs for the treatment of parasitic diseases, such as malaria and helminth
infections. Peroxides having antitumor or growth-regulatory activity were also
documented. Traditionally organic peroxides are applied in industry as initiators of
free radical polymerization and oxidants. In our work, we developed new and green
methods for synthesis of various types of peroxides using hydrogen peroxide and
carbonyl compounds.
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Biography
Alexander O Terent’ev has completed his MS in Chemistry of
Biologically Active Compounds from D Mendeleev University of
Chemical Technology of Russia, Moscow, PhD degree in 2000
and DSc degree in Organic Chemistry in N D Zelinsky Institute
of Organic Chemistry RAS 2009. He worked as Professor in D
Mendeleev University of Chemical Technology of Russia 2011.
From 2016, he is working as Professor and Head of laboratory
in N D Zelinsky Institute of Organic Chemistry RAS, Head of
laboratory in All-Russian Research Institute of Phytopathology.
His interests are Organic Chemistry, Medical and Agricultural
Chemistry, Chemical Technology. He has published three
chapters in books, 100 research papers, and 25 patents.
alterex@yandex.ruCyclic synthetic peroxides as a base for
antiparasitic and anticancer drugs
Alexander O Terent’ev
1
, Peter S Radulov
2
,
Anatoliy E Vilikotskiy
3
, Yulia Yu Belyakova
3
N D Zelinsky Institute of Organic Chemistry, Russian Academy
of Sciences, Moscow, Russia
D Mendeleev University of Chemical Technology of Russia
Moscow, Russia
Alexander O Terent’ev et al., J Org Inorg Chem 2018, Volume 4
DOI: 10.21767/2472-1123-C3-007
Some of prepared cyclic peroxides demonstrate good
anticancer and antiparasitic activities