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Infectious Diseases 2018
Journal of Prevention and Infection Control
ISSN: 2471-9668
Page 44
June 07-08, 2018
London, UK
8
th
Edition of International Conference on
Infectious Diseases
Introduction:
Zika virus (ZIKV) isn’t arousing public attention until
the outbreak on Yap Island of Micronesia since 2007 and the
largest known outbreak before Brazil. In South America (SA) and
Southeast of Asia (SEA), ZIKV has been circulating for a long time
except for China. ZIKV isn’t in the routine test list in the febrile sera
collected at China Point of Entry (PoE) before 2016, we deduced
that there might be existed ZIKV neglected or misdiagnosed.
Methodology:
A total of 264 sera collected fromthe febrile travelers
came fromSEAand SA in 2014 that stocked at the Biobank of China
PoE population were eligible for the study. The sera molecular
and serological methods were carried out to detect the ZIKV,
respectively. The ZIKV RNAwas amplified using a real-time RT-PCR
assay. Anti-ZIKV IgG was tested by indirect immunofluorescence
assay (IFA). To further exclude the cross-reactivity with other
flavivirus, conventional CPE-based micro neutralization (MN) test
were used to determine the ZIKV specific antibody.
Results:
The results showed although no ZIKV RNA found in the
stocked sera, however, 5.3% of the samples were positive for anti-
ZIKV IgG. The epidemiologic study showed ZIKV infection was
related with age and gender significantly (p<0.05), affecting the
relatively young and female population. The travelers who infected
ZIKV were consistent with the reported endemic areas.
Conclusion:
It’s deduced that the international travelers might be
as a sentinel for surveillance the ZIKV international transmission.
Recent Publications
1. Xiao Lili, Guo Hui, Sun Fujun, et al. (2006).
Exploration on Establishment of Surveillance System
for Adverse Events Following Immunization of
Inspection and Quarantine.Chinese Frontier Health
Quaratine,29(B08):124-125
2. Zhu Hong, Guo Hui, Zhang Yuanyuan, et al. (2005). The
Curent Situatian and Countermeasure of AIDS Tests
at Beijing port. Chinese Frontier Health Quarantine
,28(03):134-135.
3. XinHui,WangYu, et al. (2004). SequenceCharacteristics
and Subtype Analysis of HIV-1 Infected Strain among
Entry-Site Workers in Beijing. Chinese Frontier Health
Quaratine, 27(5): 261-262.
4. Zhu Hong, Li Hanping, Guo Hui, et al. (2004). Study
on subtype and sequence of partial env gene of HIV-
1 in people entering and exiting national frontiers
10(4):250-252.
5. Li Linping, Liu Chunyan, Guo Hui, et al. (2001). An
analysis if physical examination results of foreign
stduents in Beijing area in 2000. Science of travel
medicine 7(4):15-16.
Biography
Guo Hui has his expertise in Travel Medicine. He served as Director of the Port
of Hong Kong Port of the State Health Inspection and Quarantine Bureau; Direc-
tor of the International Travel Health Center of Beijing Entry-Exit Inspection and
Quarantine Bureau; Deputy Director of the Ministry of Industry and Communica-
tions, Director of the Department of Agricultural and Food Standards, Director
of the International Cooperation Department. He is the Director of Public Health
and Quarantine Supervision Department of AQSIQ.
Guoh@aqsiq.gov.cnPotential infection of Zika virus in the travelers detected at
the point of entry China by a retrospective study
Guo Hui
1
, Jin Xia
1
, Wang jing
2
, Liu yang
3
, Guo wenxiu
4
, Tian feng
5
, Yang Yu
2
, Zhang
Xiaolong
2
and
Liu lijuan
2
1
General Administration of Quality Supervision, Inspection and Quarantine of the PRC, China
2
Chinese Academy of Inspection and Quarantine, China
3
Jilin International Travel Healthcare Center, China
4
Inner-Mongolia International Travel Healthcare Center, China
5
Xinjiang International Travel Healthcare Center, China
Guo Hui et al., J Prev Infect Cntrol 2018, Volume 4
DOI: 10.21767/2471-9668-C1-003