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Volume 4
Trends in Green Chemistry
ISSN: 2471-9889
Page 91
JOINT EVENT
Environmental Chemistry 2018 &
Green Technologies 2018
September 20-22, 2018
September 20-22, 2018 Berlin, Germany
&
7
th
Edition of International Conference on
Green Energy, Green Engineering and Technology
8
th
International Conference on
Environmental Chemistry and Engineering
Catalytic dehydration of modified carbohydrates as a new approach to efficient biomass utilization in
organic synthesis
Konstantin I Galkin
N D Zelinsky Institute of Organic Chemistry-RAS, Russia
I
ntegration of renewable bio-resources for sustainable applications is one of the key challenges of modern chemical
science and technology. The most perspective approach to the synthetic utilization of plant biomass involves the catalytic
conversion of carbohydrates to low-molecular-weight building blocks, which are defined as bio-based platform chemicals.
5-(Hydroxymethyl) furfural (HMF) is one of the key platform chemical that can be used for a wide range of applications. Low
stability and difficult isolation process limits utilization of HMF as a reagent in organic synthesis (Figure 1, a). This presentation
will introduce an efficient approach to the preparation of stable HMF analogues by direct conversion of modified carbohydrates
(figure 1, b). A highly efficient biomass conversion process based on introduction of a silyl protecting group to glucose allowed
to significantly increase the selectivity of furan formation and facilitated its isolation from the reaction mixture. New aspects of
synthesis and utilization of HMF and derivatives for biofuels, materials and pharmaceuticals production were also described.
We have shown that the aldehyde group in HMF can be easily modified into an alkyne fragment using the Ohira-Bestmann
reaction. A number of polyunsaturated products from alkynyl furans were prepared using rhodium catalysis. The first example
of the Diels-Alder reaction of un-substituted 2, 5-bis (hydroxy methyl) furan with maleimide was carried out under green
conditions with high diastereo selectivity. The implementation of described synthetic approaches opens new opportunities for
the synthesis of demanded functional derivatives from bio-based furans.
glkn.ioc@gmail.comTrends in Green chem 2018, Volume 4
DOI: 10.21767/2471-9889-C2-012