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Dental Treatment 2018
Dentistry and Craniofacial Research
ISSN: 2576-392X
Page 50
September 10-11, 2018
Zurich, Switzerland
25
th
International Conference on
Dental Treatment
Introduction:
Oral andsystemicmanifestationsarecommon inHIV/
AIDS and are considered to be important predictors of the disease.
CD4 count serves as an important marker for the progression of
HIV to AIDS. Our objective was to correlate the oral and systemic
manifestations associated with HIV infection with CD4 count in
patient’s on HAART.
Materials & Methods:
This was an observational study among one
hundred and ten HIV diagnosed patients. The oral and systemic
manifestations were noted and compared to their CD4 counts.
Chi-square analysis was carried out to see the association of oral
manifestations. P<0.05 was considered statistically significant.
Results:
Among the 110, fifty had CD4 count >500 cells/µL, 46
patients had between CD4 count between 200-499 cells/µL and
fourteenhad<200cells/µL. AmongpatientswithCD4>500, theoral
manifestations observed are as follows, dental caries (n=30, 60%)
periodontitis and lipoatrophy (n=25, 50%) and inCD4count between
200-499, dental caries (n=28, 60.9%) intraoral pigmentation (n=23,
50%), periodontitis (n=20, 43.5%) and with subjects with CD4
count. The most common systemic manifestation observed were
tuberculosis (p<0.001) and pneumonia (p<0.003).
Clinical Significance:
Prevalence of oral and systemic
manifestations among HIV infected patients have declined since
the advent of highly active antiretroviral therapy (HAART). Oral
and general physicians should be able to identify and treat the
patients at the earliest, which in turn could reduce the morbidity
and mortality rates among those infected with HIV.
Biography
Ceena Denny has completed her Master’s degree in Oral Medicine and Ra-
diology from Bapuji Dental College and Hospital, Davangere in the year 2006
and is currently working in Manipal College of Dental Sciences, affiliated to
Manipal Academy of Higher Education as an Associate Professor in the Oral
Medicine and Radiology. She hasmore than 40 publications in various national
and international journals and has also presented research papers in national
and international conferences. She has authored chapter in text book of Oral
Medicine and Radiology published by Elsevier’s science. She frequently con-
duct lecture in CBCT as a part of certificate programme.
ceena.denny@manipal.eduOral and systemic manifestations and its relation to CD4
counts in HIV patients on HAART-an observational study
Ceena Denny
Manipal Academy of Higher Education, India
Ceena Denny, J Dent Craniofac Res 2018, Volume 3
DOI: 10.21767/2576-392X-C3-009