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Dental Treatment 2018
Dentistry and Craniofacial Research
ISSN: 2576-392X
Page 49
September 10-11, 2018
Zurich, Switzerland
25
th
International Conference on
Dental Treatment
T
rigeminal neuralgia (TN) is a chronic neuropathic pain disorder
that makes daily life difficult. Recently, Gamma Knife surgery
(GKS) has been employed for treating intractable pain control
such as trigeminal neuralgia (TN) or cancer pain. Nine patients (4
males and 5 females) with TN of second branch were investigated
in this study. All patients (mean age: 66.7±7.5) were irradiated a
maximum dose of 90 Gy at retrogasserian after the target area
were coordinated with magnetic resonance imaging (MRI) and
computed tomography (CT). They were asked symptom, medical
history and what induces the pain attack. We also assessed visual
analog scale (VAS) of pain, presence or absence of allodynia, cold
sensation dullness and touch threshold on the lateral of nasal wing
using Semmes-Weinstein monofilaments before and 1, 3, 6, and
12 months after GKS. The relation of the pain value and touch
threshold were estimated. There were two kinds of pain character,
like an electric shock (5 patients) and like prickling (4 patients).
The mean±SD of pain VAS value was 8.5±1.4 and touch threshold
on disease side (6.0±2.8 gf/mm
2
) was significant higher than the
healthy side (3.7±1.3 gf/mm
2
) at first visiting (paired t-test; P<0.05).
All patients experienced a significant pain reduction without side
affections within 6 month after GKS. Allodynia, facial paresthesia
or cold sensation dullness occurred before GKS disappeared
within 3 months after treatment. However, there was no correlation
between pain value and touch threshold. These results suggest
that GKS is safe and effective method to let a pain and dysesthesia
due to TN disappear. There are individual differences in these
effects after treatment.
Biography
Mihoko Tomida has graduated from School of Dentistry at Asahi University
and Graduate School of Medicine, Gifu University and acquired PhD. After hav-
ing worked as an Oral Surgeon for four years; she became a teacher of Physiol-
ogy. And she started to investigate the relationship between pain and emotion
by using rat and human. She found that the pain was involved with nerve cells
of an amygdala and the cingulate cortex from animal experiment. It was clear
that listening to music reduces the pain perception from human experiment.
However, the reason is unclear. Now, she looks into the relation between pain
threshold and autonomic nerve activity.
mtomi@po.mdu.ac.jpThe pain value and touch threshold of patient with trigeminal
neuralgia – the effect of Gamma Knife stereotactic
radiosurgery
Mihoko Tomida
1
, Motohiro Hayashi
2
, Ryutaro Uchikawa
1
, Soichiro Tsuchiya
1
, Keiichi
Uchida
1
and
Kosaku Ueno
3
1
Matsumoto Dental University, Japan
2
Tokyo Women’s Medical University, Japan
3
Ueno Dental Clinic, Japan
Mihoko Tomida et al., J Dent Craniofac Res 2018, Volume 3
DOI: 10.21767/2576-392X-C3-009