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E u r o S c i C o n C o n f e r e n c e o n
Dental & Dental
Hygiene
Dental & Dental Hygiene 2018
Journal of Dental and Craniofacial Research
ISSN 2576-392X
M a r c h 2 6 - 2 7 , 2 0 1 8
E d i n b u r g h , S c o t l a n d
Page 52
S
uccessful transplantation of organs depends on the quality of the donor
organ, surgical procedure and proper immunosuppressive regimen.
Immunosuppressive therapy in transplantology is divided due to its duration
and indications in three groups–induction therapy, maintenance therapy and
anti-rejection treatment. Immunosuppressants are medicants with a range of
effects, some of them are adverse. Use of immunosuppressants can cause
reactivation of virus disease or can lead to oral candidiasis manifestation due
to its infuence on immunity. Long-term immunosuppression consists mainly
inhibitors of calcineurin-tacrolimus or cyclosporin A, usually in combination
with steroids or other immunosuppressants. Tacrolimus is one of the main
immunosuppressants in transplantology. Nystatin is a well-known antifungal
drug. We would like to present some experiences with using nystatin
suspension in treatment of oral candidiasis in transplanted patients with
combined immunosuppressive therapy (mainly consist from tacrolimus and
steroids).
Tacrolimus as a potential risk of oral candidiasis
Markéta Janovská
Charles University, Czech Republic
Markéta Janovská, J Den Craniofac Res 2018, Volume: 3
DOI: 10.21767/2576-392X-C1-003
Biography
Markéta Janovská completed her study from Charles Univer-
sity in Prague, and started to work in the Department of Oral
Medicine of Všeobecná fakultní nemocnice v Prague, Institute
of Dental Medicine. She is Lecturer of Medical Students of First
Faculty of Medicine, External Lecturer of Dental Hygienists and
Profimed s.r.o. in Oral Medicine. She has been a Speaker in in-
ternational symposiums – Prague Dental Days, Slovakia Dental
Days (2017), and lectures on postgraduate education courses
for Otorhynolaryngologists and Dermatologists. She cooper-
ates in research of recurrent aphthous stomatitis. She is cur-
rently preparing for her PhD studies.
Marketa.Janovska@vfn.cz