E u r o S c i C o n C o n f e r e n c e o n
Chemistry
2018
Chemistry 2018
Journal of Organic & Inorganic Chemistry
ISSN 2472-1123
F e b r u a r y 1 9 - 2 0 , 2 0 1 8
P a r i s , F r a n c e
Page 39
T
he current study was carried out on a crude ethanolic extract of bark and
stem of Beriberisbalochistanica and this plant is endemic to Balochistan.
B. balouhistanicaused in traditional medicine. Plant was collected from local
market and ethanolic extract was carried out. The ethanolic extract was tested
for Analgesic and seductive effect. Extract produced significant analgesic
effects at the dose of 500 mg/kg in the acetic acid induced writhing test
and the formalin test. Sedative effect were determine by traction test and
forced swimming test. In traction test time taken by the mice to travel iron
rod was significantly increased. In forced swimming test mobility time was
significantly decreased. Results were significantly comparable with standard
drug diazepam. In conclusion, results suggest that the ethanolic extract of
B.baluchistanica possess significant analgesic effects also possess sedative
effects.
Biography
Imdadullah is an M.Phil Scholar in Pharmacy Department, Uni-
versity of Balochistan, Quetta Pakistan. After completion of his
graduation from the same university he joined the Government
Services as Drug Inspector in Health Department, Government
of Balochistan Quetta. Since last two years he is serving in the
public sector as Secretary Provincial Quality Control Board Ba-
lochistan, Quetta.
imdadbaloch@ymail.comEvaluation of analgesic and sedative activities of Berberis baluchistanica
extract
Imdadullah
1,2
, Muhammad Younis
3
and Shafi Muhammad
4
1
Health Department, Government of Balochistan, Pakistan
2
University of Balochistan, Pakistan
3
Department of Pharmacognosy, Faculty of Pharmacy and Health Sciences, University of Ba
lochistan Quetta Pakistan.
4
Department of Pharmacology, Faculty of Pharmacy and Health Sciences, University of Ba-
lochistan Quetta Pakistan
Imdadullah, J Org Inorg Chem 2018, Volume: 4
DOI: 10.21767/2472-1123-C1-002