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E u r o S c i C o n C o n f e r e n c e o n

Chemistry

2018

Chemistry 2018

Journal of Organic & Inorganic Chemistry

ISSN 2472-1123

F e b r u a r y 1 9 - 2 0 , 2 0 1 8

P a r i s , F r a n c e

Page 39

T

he current study was carried out on a crude ethanolic extract of bark and

stem of Beriberisbalochistanica and this plant is endemic to Balochistan.

B. balouhistanicaused in traditional medicine. Plant was collected from local

market and ethanolic extract was carried out. The ethanolic extract was tested

for Analgesic and seductive effect. Extract produced significant analgesic

effects at the dose of 500 mg/kg in the acetic acid induced writhing test

and the formalin test. Sedative effect were determine by traction test and

forced swimming test. In traction test time taken by the mice to travel iron

rod was significantly increased. In forced swimming test mobility time was

significantly decreased. Results were significantly comparable with standard

drug diazepam. In conclusion, results suggest that the ethanolic extract of

B.baluchistanica possess significant analgesic effects also possess sedative

effects.

Biography

Imdadullah is an M.Phil Scholar in Pharmacy Department, Uni-

versity of Balochistan, Quetta Pakistan. After completion of his

graduation from the same university he joined the Government

Services as Drug Inspector in Health Department, Government

of Balochistan Quetta. Since last two years he is serving in the

public sector as Secretary Provincial Quality Control Board Ba-

lochistan, Quetta.

imdadbaloch@ymail.com

Evaluation of analgesic and sedative activities of Berberis baluchistanica

extract

Imdadullah

1,2

, Muhammad Younis

3

and Shafi Muhammad

4

1

Health Department, Government of Balochistan, Pakistan

2

University of Balochistan, Pakistan

3

Department of Pharmacognosy, Faculty of Pharmacy and Health Sciences, University of Ba

lochistan Quetta Pakistan.

4

Department of Pharmacology, Faculty of Pharmacy and Health Sciences, University of Ba-

lochistan Quetta Pakistan

Imdadullah, J Org Inorg Chem 2018, Volume: 4

DOI: 10.21767/2472-1123-C1-002