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I n t e r n a t i o n a l C o n f e r e n c e o n

Physicians, Surgeons and

Case Reports

November 19-20 , 2018

Par i s , France

Medical Case Reports

ISSN: 2471-8041

PSCR 2018

Eclampsia is a life threatening condition with highest mortality and morbidity characterized by uncontrolled hypertension,

unconsciousness fits albumin urea in the setting of preeclampsia.

Study:

An extensive elaborative study carried out from 2005 to 2009, to study the therapeutic and prophylactic role of magnesium

sulphate and Diazepam in Eclampsia.

Aim:

To study the role of magnesium sulphate (MgSO

) vs. Diazepam in reducing maternal mortality ratio (MMR), neonatal

mortality rate (NMR) in Eclampsia.

Study Design:

This was a comparative study. Total 500 patients of fulminant pre-eclampsia /eclampsia including booked/

unbooked patients attending Lady Willingdon Hospital were admitted, evaluated, assessed and put on MgSO

vs. Diazepam

divided in two groups. The results were compared which showed of MgSO

has superior efficacy compared to Diazepam in

improving overall mortality and morbidity in Eclampsia.

Materials & Methods:

Total 500 patients of Eclampsia were admitted and studied in Unit-2 Lady Willingdon Teaching Hospital of

King Edward Medical University Lahore managed in ICU according to a specially design proforma, protocol and were given MgSO4

and Diazepam for control of fits, Hydralazine, Labetalol and Isoket infusions for lowering blood pressure (MgSO

) A+B. Diazepam,

with multidisciplinary involvement divided in two groups, compared and followed up.

Results:

In Group A, there were 20 mothers and in Group B, 40 mothers died. It was observed that maternal mortality was

significantly higher in Group B women as compared to that of Group A. i.e. (p-value=0.005).

Conclusion:

The comparative study and of role of MgSO

vs. Diazepam in reducing mortality, morbidity in maternities, neoneties,

efficacy showed the superiorness of magenesium sulphate as compared to Diazepam without any doubt.

The study of role of magnesium sulphate vs.

Diazepam in eclampsia

Tariq Masood Khan

Lady Willingdon Hospital Lahore, Pakistan

Med Case Rep. 2018, Volume:4

DOI: 10.21767/2471-8041-C2-006