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I n t e r n a t i o n a l C o n f e r e n c e o n
Physicians, Surgeons and
Case Reports
November 19-20 , 2018
Par i s , France
Medical Case Reports
ISSN: 2471-8041
PSCR 2018
Statement of the Problem:
It’s a clinical case presentation of a male preterm infant newborn, (+31 weeks) who was delivered
in our hospital and transferred to our NICU because of prematurity, VLBW and need of respiratory support. Baby was detected
with necrotizing enterocolitis (NEC) on 5
th
day of life, shortly after start of expressed milk feeding, which was detected early by
the use of near infrared abdominal spectroscopy (NIRS). Baby was deteriorated clinically in a couple of hours and had intestinal
perforation with peritonitis. So, abdominal exploration surgery with intestinal resection and end to end anastomosis was done
urgently. Baby improved gradually and early feedings were started which were gradually increased up to full feedings with use of
human fortified milk (HMF), probiotics and prebiotics.
Findings:
The study stated the evidence-based feeding strategies guidelines for necrotizing enterocolitis (NEC) among very low
birth weight infants and role of trophic feedings, probiotics, pre-biotics, micronutrients in prophylaxis, prevention andmanagement
of NEC.
Recommendations:
Prematurity is the single greatest risk factor for NEC and avoidance of premature birth is the best way to
prevent NEC. The role of feeding in the pathogenesis of NEC is uncertain, but it seems prudent to use breast milk (when available)
and advance feedings slowly and cautiously. NEC is one of the leading causes of mortality and the most common reason for
emergent GI surgery in newborns. NEC remains a major unsolved medical challenge, for which no specific therapy exists and
its pathogenesis remains controversial. A better understanding of the pathophysiology will offer new and innovative therapeutic
approaches and future studies should be focused on the roles of the epithelial barrier, innate immunity and microbiota in this
disorder. Bioinformatics modeling is a new emerging strategy aimed at understanding the dynamics of various inflammatory
markers and their application in early diagnosis and treatment.
amr106@gmail.comNecrotizing enterocolitis in a newborn preterm
infant and role of feeding: a clinical case
report presentation
Amr I M Hawal
1
and El Atawy Khaled
2
1
Prime Health Care Group, UAE
2
Latifa Hospital, UAE
Med Case Rep. 2018, Volume:4
DOI: 10.21767/2471-8041-C2-006