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Case Reports 2018 Medical Case Reports
ISSN: 2471-8041 Page 22
May 28-29, 2018
London, UK
8th Edition of International Conference on
Clinical and Medical Case Reports
EV or Epidermodysplasia verruciformis is a genodermatosis
marked by vulnerability to epidermoysplasia verruciformis-
human papillomavirus infections leading to initial development
ofdisseminatedflatwart-likeandpityriasisversicior-likelesions.
Nearly half of all patients having EV would develop cutaneous
malignancies, leading to Bowen’s type carcinoma(invasive) and
squamous cell carcinomas insitu which happen mostly on sun-
exposed areas in the forties of fifties. A Saudi male of 55 years
came to the clinic with a chief complaint of growth extending
from his toe nail. He had this growth since one year and it was
growing in size. The growth was painless and it extended from
the hard long toe nail . Required investigations were carried
out including complete blood count, LFT, ESR and skin biopsy.
And a final diagnosis of Epidermo dysplasia verruciformis was
confirmed. Surgical treatment is substantially quite effective.
The preferred approaches include defect reconstruction with
full-thickness or split-thickness grafts, complete excision or
local flaps. The chemotherapy without or with radiotherapy, as
in our case can be beneficial in achieving tumor’s regression/
lymph nodes before surgery. Mohs micrographic surgery can
preserve the healthy tissues, which are important for these
patients afflicted by multiple skin cancers and having risk of
their recurrence. Another alternative option is the non-surgical
treatment. Different types of non-surgical treatment methods
are tried for treatment of EV, such as oral as well as topical
retinoids, immunotherapy, interferon, cryotherapy and electro-
desiccation. EV is essentially a genetic cancer and is of viral
origin, and might also be considered as a model of cutaneous
HPV oncognesis.
Biography
Samia Sulaiman AL-Nugali Bachelor certificate from king Saud university in
medicine and general surgery in 1987 Riyadh , Saudi Arabia ,Internship in
1988 ,In 1989 I joined ministry of health and worked as general doctor for a
year and half ,In 1991 I joined King Saud medical city and the Saudi council
,In 1998 passed both parts I and II of Arab board . I worked as specialist
doctor with experience for more than 25 years in dermatology department.
Now I am an associate consultant in King Saud Medical City. I attended lots
of internal and external conferences and workshops, Also I will attend San-
Francisco in its 6th international confers as a speaker for my case.
Epidermodysplasia verruciformis
Samia Nugali
King Saud Medical City, Saudi Arabia
Samia Nugali, Med Case Rep. 2018, Volume 4
DOI:10.21767/2471-8041-C1-002