case-reports-2018-scientifictracks-abstracts

Case Reports 2018

Medical Case Reports

ISSN: 2471-8041

Page 45

May 28-29, 2018

London, UK

Edition of International Conference on

Clinical and Medical Case Reports

t is not uncommon for men with unilateral testicular cancer to go

on to develop metachronous cancer in the contralateral testis.

Here, we present two cases of metachronous bilateral testicular

cancer. In both cases, the second occurrence of testicular cancer

arose several years after the initial cancer, and were not screened

for contralateral germ cell neoplasia

in situ

(GCNIS) upon the

first diagnosis. We also present a literature review on the need

for screening biopsies of contralateral testis for GCNIS and the

risk factors which should encourage screening. Furthermore,

we have reviewed the effect of histological classification of

the initial testicular cancer on the period of development of the

contralateral tumour and its histology. We also explore the effect

of chemotherapy on the incidence of contralateral testicular

cancer and the effectiveness of radiotherapy in the treatment of

GCNIS. We would like to conclude that screening biopsies of the

contralateral testis upon diagnosis of unilateral testicular cancer

should be encouraged as it can lead to better management of the

condition and more favourable outcomes.

Biography

Zhi Yang Low is a final year medical student at University College London

with a keen interest in research and surgery, and will be starting their foun-

dation training in July in London and Leicester respectively. Dr Dhili Arul is a

Consultant Histopathologist at the Whittington Hospital, London. Mr Sud-

hanshu Chitale is a Consultant Urologist at the Whittington Hospital, Lon-

don, and Lead for the Urology Paediatric and Joint Urology Diabetes Service

and Male Fertility. He is also an Honorary Senior Lecturer at University Col-

lege London

zhi-yang.low.12@ucl.ac.uk

Metachronous bilateral testicular cancer: two case

studies and literature review

Zhi Yang Low, Angela Yan, Dhili Arul

and

Sudhanshu Chitale

Whittington Health NHS Trust - UCL Medical School, UK

Zhi Yang Low et al., Med Case Rep. 2018, Volume 4

DOI:10.21767/2471-8041-C1-002

Figure1:

Embryonal carcinoma

in right testis in 2007

Figure 2:

Classical seminoma

in left testis in 2017