advanced-stem-cell-2018-scientifictracks

8 / 12

Advanced Stem Cell 2018 Journal of Stem Cell Biology and Transplantation
ISSN: 2575-7725 Page 30
December 03-04, 2018
Valencia, Spain
15th Edition of EuroSciCon Conference on
Advanced Stem Cell &
Regenerative Medicine
Introduction: Osteoarthritis is the fourth leading cause of
disability. Knee osteoarthritis (OA) accounts for more than 80%
of the disease burden. With the increasing life expectancy and
changes in lifestyle, the prevalence of osteoarthritis is increasing
with 100% increase in prevalence of knee osteoarthritis since the
mid-20th century.
Methods: The prospective interventional study involved 50
cases and their functional outcome of platelet rich plasma (PRP)
lignocaine mixture in osteoarthritis of the knee were assessed
by VAS (Visual Analogue Score) and WOMAC (Western Ontario
and McMaster Universities Osteoarthritis Index) score. Patients
were administered three doses of intra-articular PRP-Lignocaine
mixture and were followed up till six months. The cases of knee
OA were radiologically classified by the Kellegren Lawrence
Grade, and the functional outcome was assessed by the VAS and
WOMAC score on their follow-up visit.
Results: A significant range of change in pre-treatment WOMAC
score at 1week to6months, whichwas 9.85% to24.84%. Changes
in WOMAC score at all the follow up visits were statistically
significant (p<0.001). A subsequent decline in pre-treatment
VAS score (Pain) was also observed at follow up visits at 1 week
(1.15±0.69; 18.18%), 3months (2.07±1.03; 32.63%) and 6months
(2.29±1.29; 36.14%) respectively. Changes in pre-treatment pain
(VAS score) were found to be highly significant at all periods of
observation.
Biography
Varun Kumar Agarwal pursued his graduation as an Orthopaedic Surgeon
from Indira Gandhi Medical College and Hospital, Shimla, India. He complet-
ed his Fellowship training in Spine Surgery from Fribourg, Switzerland and is
a AOSpine Fellow - Bombay Hospital, Mumbai, India. Currently, he is working
at the Rohilkhand Medical College and Hospital, Bareilly, India.
Addition of lignocaine to platelet rich plasma
enhances symptomatic relief in the osteoarthritis
of the knee: results from 50 cases
Varun Kumar Agarwal and Rachit Mehta
Rohilkhand Medical College, India
Varun Kumar Agarwal et al., J Stem Cell Biol Transplant 2018, Volume 2
DOI: 10.21767/2575-7725-C1-002