pediatric-critical-care-world-pediatrics-2018-posters

6 / 20

Volume 4 Journal of Pediatric Care
ISSN: 2471-805X
Page 33
JOINT EVENT
Pediatric Critical Care 2018 &
World Pediatrics 2018
October 18- 20 , 2018
October 18- 20, 2018 Warsaw, Poland
&
6th International Conference on
25th World Pediatrics Conference
Pediatric Critical Care and Emergency Medicine
Association between periodontitis and early atherosclerotic vascular disease
Hyun-Duck Kim, Yoo-Been Ahn and Myung-Seop Shin
Seoul National University, South Korea
Background & Aim: We aimed to evaluate the association of periodontitis with the development of early atherosclerotic
vascular disease in Korean adults.
Methods: In this cross-sectional study, a total of 1343 adults aged over 40 years were recruited from a community-based cohort
of Yangpyeong County, Korea, during the period 2010e2014. Only dentate individuals were included in the study. Subclinical
atherosclerosis (SA) was defined as carotid intima-media thickness (cIMT) of 0.754 mm, as assessed bilaterally by B-mode
ultrasound. Peripheral arterial disease (PAD) was defined as ankle-brachial index (ABI) of 1.0, as measured by Doppler. History
of periodontitis was assessed by measuring the radiographic alveolar bone loss (RABL) on a digital dental panorama and was
classified into three groups: normal, moderate and severe periodontitis (two or more nonadjacent interproximal sites with
RABL of 4 mm and 6 mm, respectively). The associations of periodontitis with SA and PAD were evaluated by multivariable
logistic regression analysis and analysis of covariance, adjusted for age, sex, education level, tooth loss, smoking, drinking,
exercise, obesity, triglycerides, HDL, LDL, hs-CRP, diabetes and hypertension. Stratified analyses were performed to identify
specific risk groups.
Results: After controlling for confounders, severe periodontitis was associated with SA [adjusted odds ratio (AOR=1.55); 95%
confidence interval (CI): 1.07e2.24] and PAD (AOR=2.03; 95% CI: 1.05e3.93). These associations were highlighted in never-
smokers. For increasing severity of periodontitis, the adjusted mean cIMT increased (p=0.011) while that of ABI decreased
(p=0.033).
Conclusion: Our data showed that periodontitis is a substantially important risk factor for atherosclerotic vascular disease
among Korean adults.
Recent Publications
1. Lee J H, Shin Y J, Lee J H and Kim HD (2018) Association of tooth brushing and proximal cleaning with periodontal
health among Korean adults: Results from Korea National Health and Nutrition Examination Survey in year 2010 and
2012. J Clin Periodontol. 45:322-335.
2. Lee J H, Shin M S, Kim E J, Ahn Y B and KimHD (2017) The association of dietary vitamin C intake with periodontitis
among Korean adults: Results from KNHANES Ⅳ. PLOS One. 12(5):e0177074.
3. Kim H D, Shin M S, Kim H T, Kim M S and Ahn Y B (2016) Incipient periodontitis and salivary molecules among
Korean adults: association and screening ability. J Clin Periodontol. 43:1032-1040.
4. Ahn Y B, Shin M S, Han D H, Sukhbaatar M, KimM S, Shin H S and Kim H D (2016) Periodontitis is associated with
the risk of subclinical atherosclerosis and peripheral arterial disease in Korean adults. Atherosclerosis. 251:311-318.
5. Shin M S, Shin H S, Ahn Y B and Kim H D (2016) Association between periodontitis and salivary
8-hydroxydeoxyguanosine among Korean rural adults. Community Dentistry and Oral Epidemiology. 44(4):381-9.
Biography
Hyun-Duck Kim has completed his PhD at Duke University, USA. He is the Director/Professor at Duke University, USA. He has over 200 publications that have been
cited over 200 times, and his publication H-index is 20 and has been serving as an Editorial Board Member of reputed journals.
Hyun-Duck Kim et al., J Pediatr Care 2018, Volume 4
DOI: 10.21767/2471-805X-C4-015